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Term:
Parent Terms Term With Siblings Child Terms
B cell proliferation involved in immune response  
isotype switching +   
The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
mature B cell differentiation involved in immune response +   

Synonyms
Exact Synonyms: class switch recombination ;   class switching ;   isotype switch recombination
Xrefs: Wikipedia:Immunoglobulin_class_switching
Definition Sources: ISBN:0781735149

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.