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Term:
negative regulation of cell differentiation (GO:0045596)
Annotations: Rat: (809) Mouse: (799) Human: (722) Chinchilla: (648) Bonobo: (661) Dog: (337) Squirrel: (21) Pig: (495)
Parent Terms Term With Siblings Child Terms
anther wall tapetum cell differentiation +  
antipodal cell differentiation +  
bundle sheath cell differentiation 
cardiocyte differentiation +   
cell development +   
cell differentiation in hindbrain +   
cell differentiation in spinal cord +   
cell differentiation involved in embryonic placenta development +   
cell differentiation involved in kidney development +   
cell differentiation involved in phenotypic switching +   
cell differentiation involved in salivary gland development +   
cell fate commitment +   
chondroblast differentiation  
chondrocyte differentiation +   
chorionic trophoblast cell differentiation +   
collenchyma cell differentiation 
compound eye cone cell differentiation +  
corticotropin hormone secreting cell differentiation +   
ectodermal cell differentiation +   
embryo sac central cell differentiation +  
embryo sac egg cell differentiation +  
endodermal cell differentiation +   
epithelial cell differentiation +   
fat cell differentiation +   
foam cell differentiation +   
follicular dendritic cell differentiation  
G1 to G0 transition involved in cell differentiation  
generative cell differentiation 
glial cell differentiation +   
hematopoietic progenitor cell differentiation +   
hemocyte differentiation +  
hepatic stellate cell differentiation 
heterocyst differentiation 
hypothalamus cell differentiation +   
inner cell mass cell differentiation +   
leukocyte differentiation +   
Leydig cell differentiation  
lung cell differentiation +   
luteal cell differentiation 
Malpighian tubule tip cell differentiation 
mesenchymal cell differentiation +   
mesodermal cell differentiation +   
muscle cell differentiation +   
myeloid cell differentiation +   
myoblast differentiation +   
myofibroblast differentiation +   
mystery cell differentiation 
negative regulation of actin filament severing  
negative regulation of adipose tissue development  
negative regulation of age-related resistance 
negative regulation of aggregation involved in sorocarp development 
negative regulation of animal organ morphogenesis +   
negative regulation of anterior head development 
negative regulation of apical ectodermal ridge formation 
negative regulation of apoptotic process involved in development +   
negative regulation of binding of sperm to zona pellucida  
negative regulation of biomineral tissue development +   
negative regulation of blood microparticle formation +  
negative regulation of blood vessel remodeling +   
negative regulation of bone development +   
negative regulation of calcium ion export across plasma membrane  
negative regulation of calcium ion transport into cytosol +   
negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation  
negative regulation of cardiac ventricle development +   
negative regulation of cartilage development +   
negative regulation of cell activation +   
negative regulation of cell adhesion +   
negative regulation of cell adhesion molecule production  
negative regulation of cell aging +   
negative regulation of cell communication +   
negative regulation of cell cycle +   
negative regulation of cell cycle checkpoint +   
negative regulation of cell death +   
negative regulation of cell differentiation +   
Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
negative regulation of cell division +   
negative regulation of cell growth +   
negative regulation of cell population proliferation +   
negative regulation of cell wall organization or biogenesis +  
negative regulation of cellular component movement +   
negative regulation of cellular component organization +   
negative regulation of cellular hyperosmotic salinity response +  
negative regulation of cellular metabolic process +   
negative regulation of cellular pH reduction +   
negative regulation of cellular response to alcohol +  
negative regulation of cellular response to alkaline pH +  
negative regulation of cellular response to drug +   
negative regulation of cellular response to gamma radiation 
negative regulation of cellular response to growth factor stimulus +   
negative regulation of cellular response to heat  
negative regulation of cellular response to hypoxia +   
negative regulation of cellular response to insulin stimulus +   
negative regulation of cellular response to macrophage colony-stimulating factor stimulus +   
negative regulation of cellular response to manganese ion 
negative regulation of cellular response to oxidative stress +   
negative regulation of cellular response to oxidopamine 
negative regulation of cellular response to testosterone stimulus  
negative regulation of cellular response to thapsigargin  
negative regulation of cellular response to tunicamycin  
negative regulation of cellular response to very-low-density lipoprotein particle stimulus 
negative regulation of cellular response to X-ray 
negative regulation of chitin-based cuticle tanning +  
negative regulation of chromosome segregation +   
negative regulation of conjugation +  
negative regulation of cuticle pigmentation +  
negative regulation of cytolysis +   
negative regulation of dense core granule biogenesis  
negative regulation of determination of dorsal identity  
negative regulation of development of symbiont involved in interaction with host +   
negative regulation of developmental growth +   
negative regulation of early endosome to late endosome transport  
negative regulation of eclosion 
negative regulation of ectoderm development +   
negative regulation of embryonic development +   
negative regulation of endocytic recycling  
negative regulation of entry into reproductive diapause 
negative regulation of epidermis development +   
negative regulation of epithelial cell proliferation involved in prostate gland development  
negative regulation of establishment of bipolar cell polarity 
negative regulation of establishment or maintenance of cell polarity regulating cell shape +  
negative regulation of female pigmentation 
negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation  
negative regulation of gene silencing +   
negative regulation of germinal center formation  
negative regulation of Golgi to plasma membrane protein transport +   
negative regulation of gonad development +   
negative regulation of heart induction +   
negative regulation of hemopoiesis +   
negative regulation of insulin receptor signaling pathway involved in determination of adult lifespan 
negative regulation of iron export across plasma membrane  
negative regulation of iron ion import across plasma membrane  
negative regulation of isotype switching +   
negative regulation of kidney development +   
negative regulation of lactation  
negative regulation of lamellipodium morphogenesis  
negative regulation of leaf development +  
negative regulation of lens epithelial cell proliferation 
negative regulation of lung alveolus development 
negative regulation of male pigmentation 
negative regulation of mammary gland development in males by androgen receptor signaling pathway 
negative regulation of mammary gland epithelial cell proliferation  
negative regulation of mammary stem cell proliferation 
negative regulation of melanosome transport 
negative regulation of mesenchymal cell proliferation involved in lung development  
negative regulation of mesenchymal cell proliferation involved in ureter development  
negative regulation of mesoderm development +   
negative regulation of mitochondrial fission  
negative regulation of mitochondrial fusion  
negative regulation of morphogenesis of an epithelium +   
negative regulation of muscle organ development +   
negative regulation of muscle tissue development +   
negative regulation of myelination  
negative regulation of nematode male tail tip morphogenesis 
negative regulation of nervous system development +   
negative regulation of nodal signaling pathway involved in determination of left/right asymmetry +   
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization  
negative regulation of peroxidase activity +   
negative regulation of pharynx morphogenesis 
negative regulation of phenotypic switching +   
negative regulation of plant organ morphogenesis +   
negative regulation of post-embryonic development +  
negative regulation of potassium ion export across plasma membrane  
negative regulation of protein folding +   
negative regulation of response to DNA damage stimulus +   
negative regulation of response to endoplasmic reticulum stress +   
negative regulation of retina development in camera-type eye +   
negative regulation of ribosome biogenesis +   
negative regulation of sclerotium development 
negative regulation of secretion by cell +   
negative regulation of sequestering of calcium ion +   
negative regulation of sequestering of zinc ion 
negative regulation of shoot apical meristem development 
negative regulation of single-species biofilm formation +   
negative regulation of sodium ion export across plasma membrane  
negative regulation of spore germination +  
negative regulation of spore-bearing organ development +  
negative regulation of sporulation +  
negative regulation of stem cell population maintenance +   
negative regulation of stomatal opening 
negative regulation of synaptic vesicle lumen acidification 
negative regulation of syncytium formation by plasma membrane fusion +   
negative regulation of thyroid gland epithelial cell proliferation  
negative regulation of tolerance induction +   
negative regulation of transposition +   
negative regulation of trophoblast cell migration  
negative regulation of tube lumen cavitation 
negative regulation of vascular smooth muscle cell dedifferentiation 
negative regulation of vasculature development +   
negative regulation of vesicle docking +  
negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis  
negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification  
negative regulation of Wnt signaling pathway involved in heart development +   
negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane 
neurogenesis +   
neuromast mantle cell differentiation +  
neuromast support cell differentiation +  
neuron differentiation +   
notochord cell differentiation +   
oenocyte differentiation +  
oocyte differentiation +   
osteoblast differentiation +   
pancreatic epsilon cell differentiation +   
pericyte cell differentiation +   
pigment cell differentiation +   
pigment cell precursor differentiation 
plant epidermal cell differentiation +   
plant parenchymal cell differentiation +  
pollen sperm cell differentiation 
positive regulation of cell differentiation +   
prolactin secreting cell differentiation +   
regulation of antipodal cell differentiation +  
regulation of cardiac endothelial to mesenchymal transition +   
regulation of cardiocyte differentiation +   
regulation of cell development +   
regulation of cell differentiation +   
regulation of cell differentiation involved in embryonic placenta development +   
regulation of cell differentiation involved in phenotypic switching +   
regulation of cell differentiation involved in tissue homeostasis 
regulation of cell fate commitment +   
regulation of chondrocyte differentiation +   
regulation of embryo sac central cell differentiation +  
regulation of embryo sac egg cell differentiation +  
regulation of endodermal cell differentiation +   
regulation of epithelial cell differentiation +   
regulation of epithelial to mesenchymal transition +   
regulation of fat cell differentiation +   
regulation of hematopoietic progenitor cell differentiation +   
regulation of hemocyte differentiation +  
regulation of leukocyte differentiation +   
regulation of macrophage derived foam cell differentiation +   
regulation of mesodermal cell differentiation +   
regulation of metanephric DCT cell differentiation +   
regulation of muscle cell differentiation +   
regulation of myeloid cell differentiation +   
regulation of myoblast differentiation +   
regulation of myofibroblast differentiation +   
regulation of osteoblast differentiation +   
regulation of pigment cell differentiation +   
regulation of plant epidermal cell differentiation +   
regulation of sclerenchyma cell differentiation +  
regulation of skeletal muscle cell differentiation +   
regulation of sorocarp spore cell differentiation +  
regulation of sorocarp stalk cell differentiation +  
regulation of sporulation resulting in formation of a cellular spore +  
regulation of stem cell differentiation +   
regulation of synergid differentiation +  
regulation of tendon cell differentiation +   
regulation of timing of cell differentiation +   
regulation of transdifferentiation +   
regulation of vasculogenesis +   
renal filtration cell differentiation +   
rhombomere cell differentiation 
sclerenchyma cell differentiation +  
sieve element differentiation +  
skeletal muscle cell differentiation +   
somatotropin secreting cell differentiation +   
sorocarp spore cell differentiation +  
sorocarp stalk cell differentiation +  
spermatid differentiation +   
sporocyte differentiation +  
sporulation resulting in formation of a cellular spore +  
stem cell differentiation +   
synergid differentiation +  
tendon cell differentiation +   
tracheary element differentiation +  
transdifferentiation +   
trichome differentiation +  
trophectodermal cell differentiation +   
vasculogenesis +   
vegetative cell differentiation 

Synonyms
Exact Synonyms: down regulation of cell differentiation ;   downregulation of cell differentiation
Narrow Synonyms: inhibition of cell differentiation
Definition Sources: GOC:go_curators

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.