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Ontology Browser

Term:
negative regulation of G protein-coupled receptor signaling pathway (GO:0045744)
Annotations: Rat: (60) Mouse: (59) Human: (54) Chinchilla: (48) Bonobo: (53) Dog: (24) Squirrel: (1) Pig: (32)
Parent Terms Term With Siblings Child Terms
adrenergic receptor signaling pathway +   
angiotensin-activated signaling pathway +   
apelin receptor signaling pathway  
bombesin receptor signaling pathway  
calcitonin family receptor signaling pathway +   
cannabinoid signaling pathway +   
cholecystokinin signaling pathway +   
complement component C5a signaling pathway  
cross-receptor inhibition within G protein-coupled receptor heterodimer  
endothelin receptor signaling pathway +   
extracellular negative regulation of signal transduction +   
follicle-stimulating hormone signaling pathway  
G protein-coupled acetylcholine receptor signaling pathway +   
G protein-coupled glutamate receptor signaling pathway +   
G protein-coupled purinergic receptor signaling pathway +   
G protein-coupled receptor signaling in absence of ligand 
G protein-coupled receptor signaling pathway involved in dauer larval development 
G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium 
G protein-coupled receptor signaling pathway involved in heart process +   
G protein-coupled receptor signaling pathway involved in social behavior 
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +   
G protein-coupled serotonin receptor signaling pathway +   
gamma-aminobutyric acid signaling pathway  
gastric inhibitory peptide signaling pathway  
ion channel modulating, G protein-coupled receptor signaling pathway +  
leukotriene signaling pathway  
luteinizing hormone signaling pathway +   
metarhodopsin inactivation 
modulation by symbiont of host G protein-coupled receptor signal transduction +  
negative adaptation of signaling pathway +   
negative regulation by symbiont of host cAMP-mediated signal transduction +  
negative regulation by symbiont of host salicylic acid-mediated defense response +  
negative regulation of abscisic acid-activated signaling pathway 
negative regulation of anti-Mullerian hormone signaling pathway  
negative regulation of antigen receptor-mediated signaling pathway +   
negative regulation of apolipoprotein A-I-mediated signaling pathway 
negative regulation of apoptotic signaling pathway +   
negative regulation of auxin mediated signaling pathway 
negative regulation of brain-derived neurotrophic factor receptor signaling pathway +   
negative regulation of brassinosteroid mediated signaling pathway 
negative regulation of CD40 signaling pathway  
negative regulation of chemorepellent activity 
negative regulation of corticotropin-releasing hormone receptor activity  
negative regulation of cytokine activity +   
negative regulation of cytokine-mediated signaling pathway +   
negative regulation of cytokinin-activated signaling pathway 
negative regulation of dopamine receptor signaling pathway +   
negative regulation of endoplasmic reticulum unfolded protein response +   
negative regulation of ephrin receptor signaling pathway 
negative regulation of ERBB signaling pathway +   
negative regulation of excitatory postsynaptic potential +   
negative regulation of Fas signaling pathway  
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis  
negative regulation of fibroblast growth factor receptor signaling pathway +   
negative regulation of G protein-coupled receptor signaling pathway +   
Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.
negative regulation of gibberellic acid mediated signaling pathway 
negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation  
negative regulation of glucocorticoid mediated signaling pathway  
negative regulation of glucose mediated signaling pathway +  
negative regulation of glutamate receptor signaling pathway +   
negative regulation of growth hormone activity 
negative regulation of growth hormone receptor signaling pathway  
negative regulation of hepatocyte growth factor receptor signaling pathway  
negative regulation of hypoxia-inducible factor-1alpha signaling pathway  
negative regulation of insulin receptor signaling pathway +   
negative regulation of insulin-like growth factor receptor signaling pathway  
negative regulation of integrin-mediated signaling pathway  
negative regulation of intracellular signal transduction +   
negative regulation of intracellular steroid hormone receptor signaling pathway +   
negative regulation of lipopolysaccharide-mediated signaling pathway +   
negative regulation of nerve growth factor receptor activity 
negative regulation of netrin-activated signaling pathway  
negative regulation of neuronal signal transduction 
negative regulation of neurotrophin TRK receptor signaling pathway  
negative regulation of Notch signaling pathway +   
negative regulation of osmosensory signaling pathway 
negative regulation of peptidoglycan recognition protein signaling pathway 
negative regulation of peroxisome proliferator activated receptor signaling pathway  
negative regulation of platelet-derived growth factor receptor signaling pathway +   
negative regulation of receptor signaling pathway via STAT +   
negative regulation of red or far-red light signaling pathway 
negative regulation of retinoic acid receptor signaling pathway  
negative regulation of Roundabout signaling pathway +  
negative regulation of semaphorin-plexin signaling pathway 
negative regulation of sevenless signaling pathway 
negative regulation of signal transduction by receptor internalization +  
negative regulation of signal transduction in absence of ligand +   
negative regulation of signal transduction in response to host +  
negative regulation of signal transduction involved in conjugation with cellular fusion +  
negative regulation of smoothened signaling pathway +   
negative regulation of sphingolipid mediated signaling pathway 
negative regulation of SREBP signaling pathway +   
negative regulation of thyroid hormone mediated signaling pathway 
negative regulation of Toll signaling pathway  
negative regulation of toll-like receptor signaling pathway +   
negative regulation of torso signaling pathway 
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +   
negative regulation of vascular endothelial growth factor receptor signaling pathway  
negative regulation of vascular endothelial growth factor signaling pathway  
negative regulation of vitamin D receptor signaling pathway  
negative regulation of Wnt signaling pathway +   
neuropeptide signaling pathway +   
octopamine or tyramine signaling pathway +  
opioid receptor signaling pathway +   
phospholipase C-activating G protein-coupled receptor signaling pathway +   
phospholipase C-inhibiting G protein-coupled receptor signaling pathway  
phospholipase D-activating G protein-coupled receptor signaling pathway  
positive regulation of G protein-coupled receptor signaling pathway +   
protein kinase C deactivation  
protein kinase C-activating G protein-coupled receptor signaling pathway  
regulation of adenosine receptor signaling pathway +   
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +   
regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway +   
regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway +   
regulation of angiotensin-activated signaling pathway +   
regulation of beta1-adrenergic receptor activity +  
regulation of endocannabinoid signaling pathway  
regulation of G protein-coupled receptor internalization +   
regulation of G protein-coupled receptor signaling pathway +   
regulation of G protein-coupled receptor signaling pathway in response to host +  
regulation of inhibitory G protein-coupled receptor phosphorylation +   
regulation of octopamine or tyramine signaling pathway +  
regulation of opioid receptor signaling pathway +   
regulation of phospholipase C-activating G protein-coupled receptor signaling pathway +   
regulation of proteinase activated receptor activity +   
regulation of rhodopsin mediated signaling pathway +   
regulation of thrombin-activated receptor signaling pathway +   
rhodopsin mediated signaling pathway +   
somatostatin receptor signaling pathway +   
sphingosine-1-phosphate receptor signaling pathway  
tachykinin receptor signaling pathway +   
termination of signal transduction +   
thrombin-activated receptor signaling pathway +   
thromboxane A2 signaling pathway  
thyroid-stimulating hormone signaling pathway  

Synonyms
Exact Synonyms: down regulation of G-protein coupled receptor protein signaling pathway ;   downregulation of G-protein coupled receptor protein signaling pathway ;   negative regulation of G protein coupled receptor protein signaling pathway ;   negative regulation of G protein coupled receptor protein signalling pathway ;   negative regulation of GPCR protein signaling pathway ;   negative regulation of GPCR protein signalling pathway
Narrow Synonyms: inhibition of G-protein coupled receptor protein signaling pathway
Definition Sources: GOC:go_curators

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.