Ontology Browser

Term:
negative regulation of mitotic metaphase/anaphase transition (GO:0045841)
Annotations: Rat: (37) Mouse: (39) Human: (39) Chinchilla: (37) Bonobo: (38) Dog: (38) Squirrel: (37)
Parent Terms Term With Siblings Child Terms
negative regulation of exit from mitosis +   
negative regulation of G1/S transition of mitotic cell cycle +   
negative regulation of G2/M transition of mitotic cell cycle +   
negative regulation of metaphase/anaphase transition of meiotic cell cycle +   
negative regulation of mitotic metaphase/anaphase transition +   
Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
negative regulation of mitotic sister chromatid arm separation 
positive regulation of mitotic metaphase/anaphase transition +   
regulation of mitotic cell cycle spindle assembly checkpoint +   
regulation of mitotic metaphase/anaphase transition +   

Synonyms
Exact Synonyms: down regulation of mitotic metaphase/anaphase transition ;   downregulation of mitotic metaphase/anaphase transition
Narrow Synonyms: inhibition of mitotic metaphase/anaphase transition
Definition Sources: GOC:go_curators

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.