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Ontology Browser

Term:
positive regulation of smoothened signaling pathway (GO:0045880)
Annotations: Rat: (43) Mouse: (43) Human: (39) Chinchilla: (39) Bonobo: (39) Dog: (26) Squirrel: (0) Pig: (33)
Parent Terms Term With Siblings Child Terms
ciliary receptor clustering involved in smoothened signaling pathway  
induction by symbiont of host cAMP-mediated signal transduction 
mesenchymal smoothened signaling pathway involved in prostate gland development  
negative regulation of smoothened signaling pathway +   
positive adaptation of signaling pathway 
positive regulation by symbiont of host salicylic acid-mediated defense response +  
positive regulation of abscisic acid-activated signaling pathway  
positive regulation of androgen receptor activity  
positive regulation of anti-Mullerian hormone signaling pathway 
positive regulation of antigen receptor-mediated signaling pathway +   
positive regulation of apolipoprotein A-I-mediated signaling pathway 
positive regulation of apoptotic signaling pathway +   
positive regulation of auxin mediated signaling pathway 
positive regulation of brain-derived neurotrophic factor receptor signaling pathway +   
positive regulation of brassinosteroid mediated signaling pathway 
positive regulation of CD40 signaling pathway  
positive regulation of chemorepellent activity 
positive regulation of corticotropin-releasing hormone receptor activity 
positive regulation of cytokine activity  
positive regulation of cytokine-mediated signaling pathway +   
positive regulation of cytokinin-activated signaling pathway 
positive regulation of dopamine receptor signaling pathway +   
positive regulation of endoplasmic reticulum unfolded protein response +   
positive regulation of ephrin receptor signaling pathway  
positive regulation of ERBB signaling pathway +   
positive regulation of excitatory postsynaptic potential +   
positive regulation of Fas signaling pathway 
positive regulation of Fc receptor mediated stimulatory signaling pathway +   
positive regulation of fibroblast growth factor receptor signaling pathway +   
positive regulation of G protein-coupled receptor signaling pathway +   
positive regulation of gibberellic acid mediated signaling pathway 
positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation 
positive regulation of glucocorticoid mediated signaling pathway 
positive regulation of glucose mediated signaling pathway  
positive regulation of glutamate receptor signaling pathway +   
positive regulation of growth hormone activity 
positive regulation of growth hormone receptor signaling pathway  
positive regulation of hepatocyte growth factor receptor signaling pathway  
positive regulation of hypoxia-inducible factor-1alpha signaling pathway  
positive regulation of inhibitory postsynaptic potential  
positive regulation of insulin receptor signaling pathway +   
positive regulation of insulin-like growth factor receptor signaling pathway  
positive regulation of integrin-mediated signaling pathway  
positive regulation of intracellular signal transduction +   
positive regulation of intracellular steroid hormone receptor signaling pathway +   
positive regulation of lipopolysaccharide-mediated signaling pathway  
positive regulation of nerve growth factor receptor activity 
positive regulation of netrin-activated signaling pathway 
positive regulation of neuronal signal transduction 
positive regulation of neurotrophin TRK receptor signaling pathway  
positive regulation of Notch signaling pathway +   
positive regulation of pattern recognition receptor signaling pathway +   
positive regulation of peptidoglycan recognition protein signaling pathway 
positive regulation of peroxisome proliferator activated receptor signaling pathway  
positive regulation of platelet-derived growth factor receptor signaling pathway +   
positive regulation of receptor signaling pathway via STAT +   
positive regulation of red or far-red light signaling pathway 
positive regulation of retinoic acid receptor signaling pathway  
positive regulation of Roundabout signaling pathway 
positive regulation of salicylic acid mediated signaling pathway 
positive regulation of semaphorin-plexin signaling pathway +   
positive regulation of sevenless signaling pathway 
positive regulation of signal transduction by receptor internalization +  
positive regulation of signal transduction involved in conjugation with cellular fusion +  
positive regulation of smoothened signaling pathway +   
Any process that activates or increases the frequency, rate or extent of smoothened signaling.
positive regulation of sphingolipid mediated signaling pathway  
positive regulation of SREBP signaling pathway +   
positive regulation of thyroid hormone mediated signaling pathway 
positive regulation of Toll signaling pathway 
positive regulation of torso signaling pathway 
positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +   
positive regulation of vascular endothelial growth factor receptor signaling pathway  
positive regulation of vascular endothelial growth factor signaling pathway  
positive regulation of vitamin D receptor signaling pathway  
positive regulation of Wnt signaling pathway +   
regulation of smoothened signaling pathway +   
regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +   
signal transduction downstream of smoothened +   
smoothened signaling pathway involved in dorsal/ventral neural tube patterning +   
smoothened signaling pathway involved in growth plate cartilage chondrocyte development 
smoothened signaling pathway involved in lung development 
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation  
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation  
smoothened signaling pathway involved in ventral spinal cord patterning +   

Synonyms
Exact Synonyms: positive regulation of hedgehog signaling pathway ;   positive regulation of hh signaling pathway ;   positive regulation of smoothened signalling pathway ;   up regulation of smoothened signaling pathway ;   upregulation of smoothened signaling pathway
Narrow Synonyms: activation of smoothened signaling pathway ;   stimulation of smoothened signaling pathway
Related Synonyms: positive regulation of smoothened by patched ;   positive regulation of smoothened receptor activity by patched
Alternate IDs: GO:0045878
Definition Sources: GOC:go_curators

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.