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Ontology Browser

Term:
isotype switching to IgA isotypes (GO:0048290)
Annotations: Rat: (9) Mouse: (8) Human: (7) Chinchilla: (6) Bonobo: (7) Dog: (6) Squirrel: (0) Pig: (6)
Parent Terms Term With Siblings Child Terms
isotype switching +     
isotype switching to IgA isotypes +   
The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.
isotype switching to IgD isotypes +  
isotype switching to IgE isotypes +   
isotype switching to IgG isotypes +   
negative regulation of isotype switching +   
positive regulation of isotype switching +   
regulation of isotype switching +   

Synonyms
Exact Synonyms: class switching to IgA isotypes ;   isotype switch recombination to IgA isotypes
Definition Sources: ISBN:0781735149, PMID:12370374, PMID:2113175, PMID:9186655

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.