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Ontology Browser

isotype switching to IgD isotypes (GO:0048292)
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Parent Terms Term With Siblings Child Terms
isotype switching +     
isotype switching to IgA isotypes +   
isotype switching to IgD isotypes +  
The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus.
isotype switching to IgE isotypes +   
isotype switching to IgG isotypes +   
negative regulation of isotype switching +   
positive regulation of isotype switching +   
regulation of isotype switching +   

Exact Synonyms: class switching to IgD isotypes ;   isotype switch recombination to IgD isotypes
Definition Sources: ISBN:0781735149, PMID:12370374, PMID:2113175, PMID:9186655

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.