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Ontology Browser

Term:
tryptophan 2'-dioxygenase activity (GO:0050360)
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Parent Terms Term With Siblings Child Terms
1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity 
1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity 
1,2-dihydroxy-8-methylnaphthalene dioxygenase activity 
1,2-dihydroxynaphthalene dioxygenase activity 
2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity 
2,4,5-trichlorophenoxyacetic acid oxygenase activity 
3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity 
inositol oxygenase activity  
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +  
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen +   
tryptophan 2'-dioxygenase activity 
Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3.

Synonyms
Exact Synonyms: L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving) ;   indole-3-alkane alpha-hydroxylase activity ;   indolyl-3-alkan alpha-hydroxylase activity
Related Synonyms: TSO I ;   TSO II ;   TSO activity ;   tryptophan side chain oxidase II ;   tryptophan side chain oxidase type I ;   tryptophan side-chain alpha,beta-oxidase activity ;   tryptophan side-chain oxidase activity
Xrefs: EC:1.13.99.3 ;   MetaCyc:TRYPTOPHAN-2-DIOXYGENASE-RXN ;   RHEA:22620
Definition Sources: EC:1.13.99.3, MetaCyc:TRYPTOPHAN-2-DIOXYGENASE-RXN

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.