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Ontology Browser

Term:
negative regulation of protein metabolic process (GO:0051248)
Annotations: Rat: (1171) Mouse: (1073) Human: (1088) Chinchilla: (1007) Bonobo: (1052) Dog: (610) Squirrel: (31) Pig: (802)
Parent Terms Term With Siblings Child Terms
amyloid fibril formation +   
amyloid precursor protein metabolic process +   
cellular protein metabolic process +   
cytochrome metabolic process +  
cytokine metabolic process +   
glycoprotein metabolic process +   
hemoglobin metabolic process +   
holo-[acyl-carrier-protein] biosynthetic process 
insulin metabolic process +   
lipoprotein metabolic process +   
low-density lipoprotein particle receptor biosynthetic process +   
metabolism by organism of protein in other organism involved in symbiotic interaction +   
negative regulation of amylopectin metabolic process +  
negative regulation of cell wall polysaccharide catabolic process +  
negative regulation of cellodextrin metabolic process +  
negative regulation of cellotriose metabolic process +  
negative regulation of cellular amide metabolic process +   
negative regulation of cellular amine metabolic process +   
negative regulation of cellulose catabolic process 
negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process 
negative regulation of cyclodextrin metabolic process +  
negative regulation of DNA metabolic process +   
negative regulation of ergot alkaloid biosynthetic process +  
negative regulation of fumitremorgin B biosynthetic process 
negative regulation of galactoglucomannan catabolic process 
negative regulation of galactomannan catabolic process 
negative regulation of gene expression +   
negative regulation of glucomannan catabolic process 
negative regulation of glycogen metabolic process +   
negative regulation of hyaluronan biosynthetic process  
negative regulation of macromolecule biosynthetic process +   
negative regulation of meiotic DNA double-strand break formation +  
negative regulation of methane biosynthetic process from dimethylamine 
negative regulation of methane biosynthetic process from methylamine 
negative regulation of methane biosynthetic process from trimethylamine 
negative regulation of methanophenazine metabolic process +  
negative regulation of methylation-dependent chromatin silencing  
negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process 
negative regulation of nitric oxide metabolic process +   
negative regulation of nitrogen cycle metabolic process +  
negative regulation of nuclease activity +   
negative regulation of nucleobase-containing compound metabolic process +   
negative regulation of pectin catabolic process 
negative regulation of phenazine biosynthetic process 
negative regulation of phosphatidylcholine biosynthetic process +   
negative regulation of phosphatidylcholine catabolic process  
negative regulation of phosphatidylserine biosynthetic process +  
negative regulation of protein metabolic process +   
Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.
negative regulation of pteridine metabolic process +  
negative regulation of quinolinate biosynthetic process  
negative regulation of receptor catabolic process +   
negative regulation of receptor internalization +   
negative regulation of receptor recycling  
negative regulation of RNA metabolic process +   
negative regulation of serotonin biosynthetic process 
negative regulation of sphingolipid biosynthetic process +   
negative regulation of starch metabolic process +  
negative regulation of tatiopterin metabolic process +  
negative regulation of terrequinone A biosynthetic process 
negative regulation of tetrapyrrole metabolic process +  
negative regulation of thiamine biosynthetic process 
negative regulation of thiamine diphosphate biosynthetic process 
negative regulation of thyroid hormone generation 
negative regulation of trypanothione biosynthetic process 
negative regulation of xyloglucan metabolic process +  
positive regulation of protein metabolic process +   
protein activation cascade +   
protein catabolic process +   
protein maturation +   
protein modification process +   
proteolysis +   
regulation of amyloid fibril formation +   
regulation of amyloid precursor protein catabolic process +   
regulation of angiotensin metabolic process  
regulation of cellular protein metabolic process +   
regulation of cytokine biosynthetic process +   
regulation of glycoprotein metabolic process +   
regulation of hemoglobin biosynthetic process +   
regulation of lipoprotein metabolic process +   
regulation of low-density lipoprotein particle receptor biosynthetic process +   
regulation of protein activation cascade +   
regulation of protein catabolic process +   
regulation of protein maturation +   
regulation of protein metabolic process +   
regulation of proteolysis +   
regulation of thymidylate synthase biosynthetic process +   
regulation of TRAIL receptor 1 biosynthetic process +  
regulation of TRAIL receptor 2 biosynthetic process +  
regulation of UDP-glucose catabolic process +   
thymidylate synthase biosynthetic process +   
TRAIL receptor 1 biosynthetic process +  
TRAIL receptor 2 biosynthetic process +  

Synonyms
Exact Synonyms: down regulation of protein metabolic process ;   downregulation of protein metabolic process ;   negative regulation of protein metabolism
Narrow Synonyms: inhibition of protein metabolic process
Definition Sources: GOC:ai

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.