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Ontology Browser

meiotic recombination checkpoint (GO:0051598)
Annotations: Rat: (3) Mouse: (4) Human: (3) Chinchilla: (3) Bonobo: (3) Dog: (3) Squirrel: (0) Pig: (3)
Parent Terms Term With Siblings Child Terms
detection of stimulus involved in meiotic cell cycle checkpoint +  
meiotic DNA integrity checkpoint +   
meiotic recombination checkpoint +   
A checkpoint that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.
meiotic spindle checkpoint +   
negative regulation of maintenance of meiotic sister chromatid cohesion +  
negative regulation of meiosis I +  
negative regulation of meiotic chromosome separation +   
negative regulation of meiotic spindle elongation 
signal transduction involved in meiotic cell cycle checkpoint +  

Exact Synonyms: pachytene checkpoint
Definition Sources: PMID:14718568

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.