Ontology Browser

Term:
negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)
Annotations: Rat: (11) Mouse: (6) Human: (12) Chinchilla: (10) Bonobo: (12) Dog: (11) Squirrel: (11)
Parent Terms Term With Siblings Child Terms
negative regulation of acetylcholine-gated cation channel activity  
negative regulation of acid-sensing ion channel activity  
negative regulation of AMPA receptor activity 
negative regulation of ATPase-coupled calcium transmembrane transporter activity  
negative regulation of calcineurin-mediated signaling +   
negative regulation of calcium:sodium antiporter activity  
negative regulation of CAMKK-AMPK signaling cascade  
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 
negative regulation of large conductance calcium-activated potassium channel activity 
negative regulation of NMDA glutamate receptor activity  
negative regulation of osmolarity-sensing cation channel activity 
negative regulation of ryanodine-sensitive calcium-release channel activity  
Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
negative regulation of store-operated calcium channel activity  
negative regulation of voltage-gated calcium channel activity +   
negative regulation of voltage-gated potassium channel activity +   
negative regulation of voltage-gated sodium channel activity 
positive regulation of ryanodine-sensitive calcium-release channel activity  

Synonyms
Definition Sources: GOC:BHF, GOC:dph, GOC:tb

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.