Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
growth hormone receptor signaling pathway via JAK-STAT (GO:0060397)
Annotations: Rat: (5) Mouse: (5) Human: (14) Chinchilla: (4) Bonobo: (4) Dog: (5) Squirrel: (3) Pig: (5)
Parent Terms Term With Siblings Child Terms
growth hormone receptor signaling pathway via JAK-STAT  
The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
negative regulation of growth hormone receptor signaling pathway  
positive regulation of growth hormone receptor signaling pathway  
regulation of growth hormone receptor signaling pathway +   

Synonyms
Exact Synonyms: JAK-STAT cascade involved in growth hormone signalling pathway
Definition Sources: GOC:BHF, GOC:dph, PMID:11445442

paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.