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Ontology Browser

Term:
canonical Wnt signaling pathway involved in ureteric bud branching (GO:0061291)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
branch elongation involved in ureteric bud branching +   
canonical Wnt signaling pathway involved in mesonephric nephron development 
canonical Wnt signaling pathway involved in ureteric bud branching 
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
dichotomous subdivision of terminal units involved in ureteric bud branching  
lateral sprouting involved in ureteric bud morphogenesis 
negative regulation of branching involved in ureteric bud morphogenesis +   
positive regulation of branching involved in ureteric bud morphogenesis  
regulation of branching involved in ureteric bud morphogenesis +   
trifid subdivision of terminal units involved in ureteric bud branching 

Synonyms
Exact Synonyms: canonical Wnt receptor signaling pathway involved in ureteric bud branching ;   canonical Wnt receptor signalling pathway involved in ureteric bud branching
Definition Sources: GOC:mtg_kidney_jan10

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.