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Ontology Browser

Term:
tRNA gene clustering (GO:0070058)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
centromere complex assembly +   
chromatin organization +   
chromosome breakage  
chromosome decondensation +  
chromosome organization involved in meiotic cell cycle +   
DNA conformation change +   
dsDNA loop formation +   
heterochromatin assembly +   
heterochromatin maintenance  
kinetochore organization +   
maintenance of DNA repeat elements +   
negative regulation of chromosome organization +   
nucleotide-excision repair, DNA damage recognition +   
polytene chromosome puffing +  
positive regulation of chromosome organization +   
regulation of chromosome organization +   
sister chromatid cohesion +   
sister chromatid segregation +   
synaptonemal complex organization +   
telomere organization +   
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery +   
tRNA gene clustering 
The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae.

Synonyms
Definition Sources: GOC:jh, GOC:mah, PMID:18708579

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.