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Ontology Browser

Term:
negative regulation of ERK1 and ERK2 cascade (GO:0070373)
Annotations: Rat: (76) Mouse: (75) Human: (69) Chinchilla: (66) Bonobo: (66) Dog: (30) Squirrel: (2) Pig: (43)
Parent Terms Term With Siblings Child Terms
inactivation of MAPKK activity  
inactivation of MAPKKK activity 
negative regulation of ERK1 and ERK2 cascade  
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
negative regulation of ERK5 cascade  
negative regulation of MAP kinase activity +   
negative regulation of MAPK cascade involved in axon regeneration 
negative regulation of stress-activated MAPK cascade +   
positive regulation of ERK1 and ERK2 cascade +   
regulation of ERK1 and ERK2 cascade +   

Synonyms
Exact Synonyms: down regulation of ERK1 and ERK2 cascade ;   downregulation of ERK1 and ERK2 cascade ;   negative regulation of ERK1 and ERK2 signaling pathway ;   negative regulation of ERK1 and ERK2 signalling pathway ;   negative regulation of ERK1/2 cascade
Narrow Synonyms: inhibition of ERK1 and ERK2 cascade ;   negative regulation of ERK1 cascade ;   negative regulation of ERK2 cascade ;   negative regulation of MAPK1 cascade ;   negative regulation of MAPK3 cascade
Broad Synonyms: negative regulation of ERK cascade
Definition Sources: GOC:add, ISBN:0121245462, ISBN:0896039986

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.