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Term:
peptidyl-lysine 5-dioxygenase activity (GO:0070815)
Annotations: Rat: (4) Mouse: (4) Human: (4) Chinchilla: (4) Bonobo: (4) Dog: (4) Squirrel: (4) Pig: (4)
Parent Terms Term With Siblings Child Terms
(gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity 
(gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity 
1-ethyladenine demethylase activity  
2'-deoxymugineic-acid 2'-dioxygenase activity 
2'-deoxymugineic-acid 3-dioxygenase activity 
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity 
2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity 
4-chloro-2-methylphenoxyacetate oxygenase activity 
4-coumaroyl 2'-hydroxylase activity 
5-formylcytosine dioxygenase activity 
5-hydroxymethylcytosine dioxygenase activity 
6-beta-hydroxyhyoscyamine epoxidase activity 
[acyl-carrier-protein] phosphodiesterase activity 
[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase 
[protein-PII] uridylyltransferase activity 
alpha-1,4-glucan-protein synthase (ADP-forming) activity 
anthocyanidin synthase activity 
biotin-protein ligase activity +   
catalytic activity, acting on a glycoprotein +   
clavaminate synthase activity 
codeine O-demethylase activity 
deacetoxycephalosporin-C hydroxylase activity 
deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity 
deoxyhypusine monooxygenase activity  
deoxyuridine 1'-dioxygenase activity 
deoxyuridine 2'-dioxygenase activity 
desacetoxyvindoline 4-hydroxylase activity 
dihydrolipoyllysine-residue acetyltransferase activity  
dihydrolipoyllysine-residue succinyltransferase activity  
DNA-N1-methyladenine dioxygenase activity  
dolichyl-phosphate-mannose-protein mannosyltransferase activity  
flavone synthase activity 
flavonol synthase activity 
FR-33289 synthase activity 
GA20 2,3-desaturase activity 
GA5 2,3 epoxidase activity 
GA5 3beta-hydroxylase activity 
gamma-butyrobetaine dioxygenase activity  
gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity 
gibberellin 2-beta-dioxygenase activity +  
gibberellin 20-oxidase activity 
gibberellin 3-beta-dioxygenase activity 
gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming) 
gibberellin A12,2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A110-forming) 
gibberellin A12,oxoglutarate:oxygen oxidoreductase activity 
gibberellin A13,oxoglutarate:oxygen oxidoreductase activity 
gibberellin A17,oxoglutarate:oxygen oxidoreductase activity 
gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity 
gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity 
gibberellin A25 hydroxylase activity 
gibberellin A25,oxoglutarate:oxygen oxidoreductase activity 
gibberellin A28,oxoglutarate:oxygen oxidoreductase activity 
gibberellin A34,2-oxoglutarate:oxygen oxidoreductase activity 
gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity 
gibberellin A51,2-oxoglutarate:oxygen oxidoreductase activity 
gibberellin A53, 2-oxoglutarate:oxygen oxidoreductase activity 
gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming) 
gibberellin A9,2-oxoglutarate:oxygen oxidoreductase activity 
gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity 
gibberellin-44 dioxygenase activity 
glutarate dioxygenase activity 
histone demethylase activity (H3-K36 specific)  
holocytochrome-c synthase activity  
hyoscyamine (6S)-dioxygenase activity 
hypophosphite dioxygenase activity 
hypoxia-inducible factor-asparagine oxygenase activity  
L-arginine 3-hydroxylase activity 
L-gamma-glutamyl-L-propargylglycine hydroxylase activity 
leucocyanidin oxygenase activity 
lipoate-protein ligase activity  
lipoyl(octanoyl) transferase activity  
methylcytosine dioxygenase activity  
microtubule plus end polymerase  
microtubule-severing ATPase activity  
mugineic-acid 3-dioxygenase activity 
N1-methyladenine demethylase activity 
N3-methylcytosine demethylase activity 
naringenin 3-dioxygenase activity 
oripavine 6-O-demethylase activity 
palmitoyl-(protein) hydrolase activity  
peptidase activity +   
peptide alpha-N-propionyltransferase activity 
peptide-aspartate beta-dioxygenase activity  
peptide-lysine-N-acetyltransferase activity +   
peptide-O-fucosyltransferase activity  
peptide-tryptophan 2,3-dioxygenase activity 
peptidyl-arginine 3-dioxygenase activity 
peptidyl-asparagine 3-dioxygenase activity  
peptidyl-aspartic acid 3-dioxygenase activity  
peptidyl-cysteine S-nitrosylase activity  
peptidyl-histidine dioxygenase activity  
peptidyl-lysine 3-dioxygenase activity 
peptidyl-lysine 4-dioxygenase activity 
peptidyl-lysine 5-dioxygenase activity +   
Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.
peptidyl-lysine N6-palmitoyltransferase activity 
peptidyl-proline dioxygenase activity +   
peptidyl-prolyl cis-trans isomerase activity  
peptidylamidoglycolate lyase activity  
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity 
phosphoprotein phosphatase activity +   
phytanoyl-CoA dioxygenase activity  
polypeptide N-acetylgalactosaminyltransferase activity  
procollagen galactosyltransferase activity  
procollagen glucosyltransferase activity  
proline 3-hydroxylase activity 
protein adenylylhydrolase activity  
protein ADP-ribosylase activity  
protein deacetylase activity +   
protein deglycase activity  
protein demethylase activity +   
protein disulfide isomerase activity  
protein kinase activity +   
protein methylesterase activity +   
protein methylthiotransferase activity 
protein methyltransferase activity +   
protein N-acetylglucosaminyltransferase activity  
protein O-GlcNAc transferase activity  
protein prenyltransferase activity +   
protein xylosyltransferase activity  
protein-cysteine S-acyltransferase activity +   
protein-fructosamine 3-kinase activity  
protein-glucosylgalactosylhydroxylysine glucosidase activity  
protein-glutamic acid ligase activity +   
protein-glycine ligase activity +   
protein-lysine 6-oxidase activity  
protein-ribulosamine 3-kinase activity  
protein-tyrosine sulfotransferase activity  
Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity 
sulfonate dioxygenase activity 
taurine dioxygenase activity 
thebaine 6-O-demethylase activity 
thebane O-demethylase activity 
thymine dioxygenase activity 
transferase activity, transferring amino-acyl groups +   
trimethyllysine dioxygenase activity  
tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity  
tubulin-tyrosine ligase activity  
ubiquitin-like modifier activating enzyme activity +   
ubiquitin-like protein transferase activity +   
ubiquitinyl hydrolase activity +   

Synonyms
Exact Synonyms: peptide-lysine 5-dioxygenase activity ;   protein lysine hydroxylase activity
Broad Synonyms: lysine hydroxylase activity ;   lysine,2-oxoglutarate 5-dioxygenase activity ;   lysine-2-oxoglutarate dioxygenase activity ;   lysyl hydroxylase activity
Related Synonyms: peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity ;   peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity
Definition Sources: PMID:19574390

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.