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Ontology Browser

Term:
protein K48-linked ubiquitination (GO:0070936)
Annotations: Rat: (64) Mouse: (66) Human: (62) Chinchilla: (57) Bonobo: (59) Dog: (62) Squirrel: (59) Pig: (65)
Parent Terms Term With Siblings Child Terms
negative regulation of protein polyubiquitination +   
positive regulation of protein polyubiquitination +   
protein K11-linked ubiquitination  
protein K27-linked ubiquitination  
protein K29-linked ubiquitination  
protein K33-linked ubiquitination  
protein K48-linked ubiquitination +   
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
protein K6-linked ubiquitination  
protein K63-linked ubiquitination +   
protein linear polyubiquitination +   
protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process 
regulation of protein polyubiquitination +   

Synonyms
Exact Synonyms: protein K48-linked polyubiquitination
Definition Sources: GOC:cvs, PMID:15556404

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.