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Ontology Browser

Term:
intrinsic apoptotic signaling pathway by p53 class mediator (GO:0072332)
Annotations: Rat: (79) Mouse: (80) Human: (84) Chinchilla: (78) Bonobo: (80) Dog: (77) Squirrel: (78) Pig: (79)
Parent Terms Term With Siblings Child Terms
DNA damage response, signal transduction by p53 class mediator +   
intrinsic apoptotic signaling pathway by p53 class mediator +   
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
intrinsic apoptotic signaling pathway in response to DNA damage +   
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +   
intrinsic apoptotic signaling pathway in response to hypoxia +   
intrinsic apoptotic signaling pathway in response to nitrosative stress +   
intrinsic apoptotic signaling pathway in response to osmotic stress +   
intrinsic apoptotic signaling pathway in response to oxidative stress +   
negative regulation of intrinsic apoptotic signaling pathway +   
negative regulation of signal transduction by p53 class mediator +   
positive regulation of intrinsic apoptotic signaling pathway +   
positive regulation of signal transduction by p53 class mediator +   
regulation of intrinsic apoptotic signaling pathway +   
regulation of signal transduction by p53 class mediator +   

Synonyms
Exact Synonyms: intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
Related Synonyms: signal transduction by p53 class mediator resulting in induction of apoptosis
Definition Sources: GOC:mah, GOC:mtg_apoptosis

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.