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Ontology Browser

Term:
protein activation cascade (GO:0072376)
Annotations: Rat: (13) Mouse: (12) Human: (27) Chinchilla: (27) Bonobo: (25) Dog: (8) Squirrel: (1) Pig: (10)
Parent Terms Term With Siblings Child Terms
amyloid fibril formation +   
amyloid precursor protein metabolic process +   
cellular protein metabolic process +   
cellular response to stimulus +   
cytochrome metabolic process +  
cytokine metabolic process +   
detection of stimulus +   
glycoprotein metabolic process +   
hemoglobin metabolic process +   
holo-[acyl-carrier-protein] biosynthetic process 
immune response +   
insulin metabolic process +   
lipoprotein metabolic process +   
low-density lipoprotein particle receptor biosynthetic process +   
metabolism by organism of protein in other organism involved in symbiotic interaction +   
muscle adaptation +   
negative regulation of protein metabolic process +   
negative regulation of response to stimulus +   
positive regulation of protein metabolic process +   
positive regulation of response to stimulus +   
protein activation cascade +   
A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.
protein catabolic process +   
protein maturation +   
protein modification process +   
proteolysis +   
regulation of protein metabolic process +   
regulation of response to stimulus +   
response to abiotic stimulus +   
response to activity +   
response to biotic stimulus +   
response to chemical +   
response to endogenous stimulus +   
response to estrogen +   
response to external stimulus +   
response to inactivity +   
response to redox state +   
response to stimulus involved in regulation of muscle adaptation +   
response to stress +   
thymidylate synthase biosynthetic process +   
TRAIL receptor 1 biosynthetic process +  
TRAIL receptor 2 biosynthetic process +  

Synonyms
Exact Synonyms: protein activation pathway ;   protein activitory cascade
Definition Sources: GOC:add, GOC:mah, GOC:pde

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.