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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
formation of extrachromosomal circular DNA involved in replicative cell aging +  
t-circle formation +   
A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD).

Synonyms
Exact Synonyms: telomeric circle formation
Definition Sources: GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:19214183, PMID:19581589, PMID:19809492, PMID:19858100

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.