Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
telomere maintenance via telomere trimming (GO:0090737)
Annotations: Rat: (8) Mouse: (8) Human: (15) Chinchilla: (14) Bonobo: (14) Dog: (6) Squirrel: (0) Pig: (6)
Parent Terms Term With Siblings Child Terms
negative regulation of telomere maintenance +   
positive regulation of telomere maintenance +   
regulation of telomere maintenance +   
telomere capping +   
telomere maintenance in response to DNA damage +   
telomere maintenance via recombination +   
telomere maintenance via semi-conservative replication +   
telomere maintenance via telomere lengthening +   
telomere maintenance via telomere trimming +   
A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication.
telomeric loop disassembly +   
telomeric loop formation +   

Synonyms
Definition Sources: GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:27918544

paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.