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Ontology Browser

Term:
phosphatidylinositol 3-kinase complex, class I (GO:0097651)
Annotations: Rat: (6) Mouse: (4) Human: (5) Chinchilla: (4) Bonobo: (4) Dog: (4) Squirrel: (4) Pig: (4)
Parent Terms Term With Siblings Child Terms
phosphatidylinositol 3-kinase complex, class I +   
A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast.
phosphatidylinositol 3-kinase complex, class II 
phosphatidylinositol 3-kinase complex, class III +   

Synonyms
Exact Synonyms: class I PI3K complex
Definition Sources: GOC:ha, PMID:24587488

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.