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Ontology Browser

Term:
negative regulation of production of siRNA involved in RNA interference (GO:1903704)
Annotations: Rat: (1) Mouse: (1) Human: (1) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1)
Parent Terms Term With Siblings Child Terms
conversion of ds siRNA to ss siRNA involved in RNA interference  
gene silencing +   
mRNA catabolic process +   
negative regulation of cytokine production +   
negative regulation of gene expression, epigenetic +   
negative regulation of histone gene expression 
negative regulation of miRNA metabolic process +   
negative regulation of mRNA metabolic process +   
negative regulation of mRNA processing +   
negative regulation of production of miRNAs involved in gene silencing by miRNA +   
negative regulation of production of siRNA involved in RNA interference  
Any process that stops, prevents or reduces the frequency, rate or extent of production of siRNA involved in RNA interference.
negative regulation of protein maturation +   
negative regulation of rhodopsin gene expression 
negative regulation of ribonuclease activity +   
negative regulation of RNA biosynthetic process +   
negative regulation of RNA catabolic process +   
negative regulation of RNA splicing +   
negative regulation of rRNA processing  
negative regulation of snoRNA metabolic process +  
negative regulation of snoRNA processing 
negative regulation of snRNA pseudouridine synthesis 
negative regulation of transcription, DNA-templated +   
negative regulation of translation +   
negative regulation of tRNA metabolic process +   
negative regulation of tRNA processing 
pericentric heterochromatin assembly +   
positive regulation of production of siRNA involved in RNA interference 
production of ta-siRNAs involved in RNA interference 
regulation of production of siRNA involved in RNA interference +   
suppression by virus of host gene expression +  

Synonyms
Exact Synonyms: down regulation of RNA interference, production of guide RNAs ;   down regulation of RNA interference, production of siRNA ;   down regulation of production of guide RNAs involved in RNA interference ;   down regulation of production of siRNA involved in RNA interference ;   downregulation of RNA interference, production of guide RNAs ;   downregulation of RNA interference, production of siRNA ;   downregulation of production of guide RNAs involved in RNA interference ;   downregulation of production of siRNA involved in RNA interference ;   negative regulation of RNA interference, production of guide RNAs ;   negative regulation of RNA interference, production of siRNA ;   negative regulation of production of guide RNAs involved in RNA interference
Narrow Synonyms: inhibition of RNA interference, production of guide RNAs ;   inhibition of RNA interference, production of siRNA ;   inhibition of production of guide RNAs involved in RNA interference ;   inhibition of production of siRNA involved in RNA interference
Definition Sources: GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19701182

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.