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Ontology Browser

Term:
negative regulation of IRE1-mediated unfolded protein response (GO:1903895)
Annotations: Rat: (6) Mouse: (4) Human: (6) Chinchilla: (4) Bonobo: (4) Dog: (4) Squirrel: (4) Pig: (5)
Parent Terms Term With Siblings Child Terms
negative regulation of ATF6-mediated unfolded protein response  
negative regulation of IRE1-mediated unfolded protein response  
Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response.
negative regulation of PERK-mediated unfolded protein response  
positive regulation of IRE1-mediated unfolded protein response  
regulation of IRE1-mediated unfolded protein response +   

Synonyms
Exact Synonyms: down regulation of IRE1 branch of UPR ;   down regulation of IRE1-mediated unfolded protein response ;   down regulation of UPR signaling by IRE1 stress sensor ;   down regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling ;   downregulation of IRE1 branch of UPR ;   downregulation of IRE1-mediated unfolded protein response ;   downregulation of UPR signaling by IRE1 stress sensor ;   downregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling ;   negative regulation of IRE1 branch of UPR ;   negative regulation of UPR signaling by IRE1 stress sensor ;   negative regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling
Narrow Synonyms: down regulation of IRE1alpha unfolded protein response ;   down regulation of IRE1p unfolded protein response ;   downregulation of IRE1alpha unfolded protein response ;   downregulation of IRE1p unfolded protein response ;   inhibition of IRE1 branch of UPR ;   inhibition of IRE1-mediated unfolded protein response ;   inhibition of IRE1alpha unfolded protein response ;   inhibition of IRE1p unfolded protein response ;   inhibition of UPR signaling by IRE1 stress sensor ;   inhibition of endoplasmic reticulum unfolded protein response; IRE1 signaling ;   negative regulation of IRE1alpha unfolded protein response ;   negative regulation of IRE1p unfolded protein response
Related Synonyms: down regulation of IRE1 signaling in response to endoplasmic reticulum stress ;   down regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction ;   downregulation of IRE1 signaling in response to endoplasmic reticulum stress ;   downregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction ;   inhibition of IRE1 signaling in response to endoplasmic reticulum stress ;   inhibition of inositol-requiring transmembrane kinase/endonuclease signal transduction ;   negative regulation of ERN1-mediated unfolded protein response ;   negative regulation of IRE1 signaling in response to endoplasmic reticulum stress ;   negative regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction
Definition Sources: GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.