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Ontology Browser

Term:
negative regulation of PERK-mediated unfolded protein response (GO:1903898)
Annotations: Rat: (3) Mouse: (3) Human: (5) Chinchilla: (3) Bonobo: (3) Dog: (3) Squirrel: (3) Pig: (3)
Parent Terms Term With Siblings Child Terms
negative regulation of ATF6-mediated unfolded protein response  
negative regulation of IRE1-mediated unfolded protein response  
negative regulation of PERK-mediated unfolded protein response  
Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.
positive regulation of PERK-mediated unfolded protein response  
regulation of PERK-mediated unfolded protein response +   

Synonyms
Exact Synonyms: down regulation of PERK branch of UPR ;   down regulation of PERK-mediated unfolded protein response ;   down regulation of PKR-like ER kinase signal transduction ;   down regulation of UPR signaling by PERK stress sensor ;   down regulation of endoplasmic reticulum unfolded protein response; PERK signaling ;   downregulation of PERK branch of UPR ;   downregulation of PERK-mediated unfolded protein response ;   downregulation of PKR-like ER kinase signal transduction ;   downregulation of UPR signaling by PERK stress sensor ;   downregulation of endoplasmic reticulum unfolded protein response; PERK signaling ;   negative regulation of PERK branch of UPR ;   negative regulation of PKR-like ER kinase signal transduction ;   negative regulation of UPR signaling by PERK stress sensor ;   negative regulation of endoplasmic reticulum unfolded protein response; PERK signaling
Narrow Synonyms: inhibition of PERK branch of UPR ;   inhibition of PERK-mediated unfolded protein response ;   inhibition of PKR-like ER kinase signal transduction ;   inhibition of UPR signaling by PERK stress sensor ;   inhibition of endoplasmic reticulum unfolded protein response; PERK signaling
Related Synonyms: down regulation of PERK signaling in response to endoplasmic reticulum stress ;   downregulation of PERK signaling in response to endoplasmic reticulum stress ;   inhibition of PERK signaling in response to endoplasmic reticulum stress ;   negative regulation of EIF2AK3-mediated unfolded protein response ;   negative regulation of PERK signaling in response to endoplasmic reticulum stress
Definition Sources: GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22013210

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.