Ontology Browser

Term:
negative regulation of NMDA glutamate receptor activity (GO:1904782)
Annotations: Rat: (2) Mouse: (2) Human: (1) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1)
Parent Terms Term With Siblings Child Terms
cross-receptor inhibition within G protein-coupled receptor heterodimer  
negative regulation of acetylcholine-gated cation channel activity  
negative regulation of acid-sensing ion channel activity  
negative regulation of advanced glycation end-product receptor activity  
negative regulation of AMPA receptor activity 
negative regulation of beta1-adrenergic receptor activity 
negative regulation of brain-derived neurotrophic factor-activated receptor activity  
negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway 
negative regulation of corticotropin-releasing hormone receptor activity  
negative regulation of epidermal growth factor-activated receptor activity  
negative regulation of GABA-A receptor activity 
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 
negative regulation of large conductance calcium-activated potassium channel activity 
negative regulation of nerve growth factor receptor activity 
negative regulation of NMDA glutamate receptor activity  
Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity.
negative regulation of osmolarity-sensing cation channel activity 
negative regulation of proteinase activated receptor activity 
negative regulation of ryanodine-sensitive calcium-release channel activity  
negative regulation of store-operated calcium channel activity  
negative regulation of voltage-gated calcium channel activity +   
negative regulation of voltage-gated potassium channel activity +   
negative regulation of voltage-gated sodium channel activity 
positive regulation of NMDA glutamate receptor activity  

Synonyms
Exact Synonyms: down regulation of N-methyl-D-aspartate selective glutamate receptor activity ;   down regulation of NMDA glutamate receptor activity ;   down regulation of NMDA receptor ;   downregulation of N-methyl-D-aspartate selective glutamate receptor activity ;   downregulation of NMDA glutamate receptor activity ;   downregulation of NMDA receptor ;   negative regulation of N-methyl-D-aspartate selective glutamate receptor activity ;   negative regulation of NMDA receptor
Narrow Synonyms: inhibition of N-methyl-D-aspartate selective glutamate receptor activity ;   inhibition of NMDA glutamate receptor activity ;   inhibition of NMDA receptor
Definition Sources: GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:12857

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.