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Ontology Browser

Term:
negative regulation of guanyl-nucleotide exchange factor activity (GO:1905098)
Annotations: Rat: (8) Mouse: (8) Human: (8) Chinchilla: (8) Bonobo: (8) Dog: (8) Squirrel: (8) Pig: (8)
Parent Terms Term With Siblings Child Terms
modulation by host of viral molecular function +   
negative regulation of binding +   
negative regulation of catalytic activity +   
negative regulation of DNA-binding transcription factor activity +   
negative regulation of guanyl-nucleotide exchange factor activity +   
Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity.
negative regulation of low-density lipoprotein receptor activity  
negative regulation of molecular function in other organism +   
negative regulation of molecular function, epigenetic 
negative regulation of nuclear receptor transcription coactivator activity  
negative regulation of RNA binding transcription factor activity 
negative regulation of signaling receptor activity +   
negative regulation of transporter activity +   
positive regulation of calcium ion binding 
positive regulation of chromatin binding +   
positive regulation of collagen binding  
positive regulation of DNA binding +   
positive regulation of ferrous iron binding  
positive regulation of GTP binding +   
positive regulation of guanyl-nucleotide exchange factor activity +   
positive regulation of heparan sulfate binding  
positive regulation of lipid binding 
positive regulation of molecular function in other organism +  
positive regulation of polysome binding  
positive regulation of protein binding +   
positive regulation of RNA binding +   
regulation of Rho guanyl-nucleotide exchange factor activity  

Synonyms
Exact Synonyms: down regulation of GDP-dissociation stimulator activity ;   down regulation of GDS ;   down regulation of GEF ;   down regulation of guanyl-nucleotide exchange factor activity ;   down regulation of guanyl-nucleotide release factor activity ;   down regulation of guanyl-nucleotide releasing factor ;   downregulation of GDP-dissociation stimulator activity ;   downregulation of GDS ;   downregulation of GEF ;   downregulation of guanyl-nucleotide exchange factor activity ;   downregulation of guanyl-nucleotide release factor activity ;   downregulation of guanyl-nucleotide releasing factor ;   negative regulation of GDP-dissociation stimulator activity ;   negative regulation of GDS ;   negative regulation of GEF ;   negative regulation of guanyl-nucleotide release factor activity ;   negative regulation of guanyl-nucleotide releasing factor
Narrow Synonyms: down regulation of GNRP ;   downregulation of GNRP ;   inhibition of GDP-dissociation stimulator activity ;   inhibition of GDS ;   inhibition of GEF ;   inhibition of GNRP ;   inhibition of guanyl-nucleotide exchange factor activity ;   inhibition of guanyl-nucleotide release factor activity ;   inhibition of guanyl-nucleotide releasing factor ;   negative regulation of GNRP
Definition Sources: GO_REF:0000059, GOC:TermGenie, PMID:20484009

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.