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Ontology Browser

Term:
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator (GO:1990127)
Annotations: Rat: (1) Mouse: (1) Human: (1) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1)
Parent Terms Term With Siblings Child Terms
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator +   
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator +   
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator +   
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress +   
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator +   
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress +   
regulation of intrinsic apoptotic signaling pathway by p53 class mediator +   
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress +   

Synonyms
Definition Sources: GOC:krc, GOC:mtg_apoptosis, PMID:16571598

paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.