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Ontology Browser

Term:
increased susceptibility to type III hypersensitivity reaction (MP:0005615)
Annotations: Rat: (3) Mouse: (8) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
decreased susceptibility to type III hypersensitivity reaction  
increased susceptibility to endotoxin shock  
increased susceptibility to type I hypersensitivity reaction  
increased susceptibility to type II hypersensitivity reaction  
increased susceptibility to type III hypersensitivity reaction  
greater likelihood of developing tissue injury mediated by immune complexes; generally involves immune complexes formed in the blood via antibodies encountering circulating antigen; Ag-Ab complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury
increased susceptibility to type IV hypersensitivity reaction  

Synonyms
Exact Synonyms: decreased resistance to immune complex mediated hypersensitivity ;   decreased resistance to type III hypersensitivity reaction ;   increased susceptibility to immune complex mediated hypersensitivity
Definition Sources: ISBN:0-397-51047-0, MGI:cwg

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.