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Ontology Browser

Term:
abnormal cumulus expansion (MP:0009373)
Annotations: Rat: (0) Mouse: (13) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
abnormal cumulus expansion +   
anomaly in the ability of the cumulus cells to synthesize and accumulate hyaluronan into an extracellular matrix (ECM), which provides an essential microenvironment for oocyte fertilization; this expanded ECM binds the oocyte and the cumulus cells together, protects the oocyte from the proteolytic and mechanical stresses during extrusion, and allows sperm binding, penetration, and fertilization
absent mature ovarian follicles  
impaired ovarian folliculogenesis  
increased follicle recruitment  

Synonyms
Exact Synonyms: abnormal ovarian cumulus expansion ;   abnormal ovarian cumulus growth
Definition Sources: MGI:anna

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.