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Study IDStudyExperiment NameExperiment NotesStrain Ont IDStrainSexAge# of AnimalsSample NotesClinical Measurement Ont IDPhenotypeFormulaClinical Measurement NotesAverage TypeValueUnitsSEMSDMethod Ont IDMethodMethod SiteMethod DurationMethod NotesPost Insult TypePost Insult Time ValuePost Insult Time UnitConditionsRecord IDCondition 1aCondition 1bCondition 2aCondition 2b
850Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89body massRS:0000154BN/SsNboth126 days to 66 days13CMO:0001399body weight loss(weight loss)0%0.00.0MMO:0000016body weighing method0.0variableimmunized10daystype II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) 69958type II collagen (2 mg/kg) Freund's incomplete adjuvant (50 %)
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8leukocyte quantityRS:0000154BN/SsNboth139 days to 132 days208CMO:0000027white blood cell count7.2x 1000 cells/ul0.08321.2MMO:0000144automated total white blood cell count test0naive control condition65939naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8leukocyte quantityRS:0000154BN/SsNboth139 days to 132 days207CMO:0000027white blood cell count9.6x 1000 cells/ul0.16262.34MMO:0000144automated total white blood cell count test0naive control condition65870naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8platelet quantityRS:0000154BN/SsNboth139 days to 132 days208CMO:0000029platelet count1037x 1000 cells/ul3.466950.0MMO:0000146automated blood cell counting method0naive control condition65927naive control condition
850Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89joint integrity traitRS:0000154BN/SsNboth126 days to 66 days13CMO:0001453percentage of study population developing experimental arthritis during a period of time0%MMO:0000163in vivo visual assessment0.0variableimmunized10daystype II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) 69961type II collagen (2 mg/kg) Freund's incomplete adjuvant (50 %)
850Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89blood immunoglobulin amountRS:0000154BN/SsNboth126 days to 66 days13CMO:0001278calculated serum anti-porcine type 2 collagen antibody titertiter30.55472.0MMO:0000075enzyme linked immunosorbent assay (ELISA)0.0variableimmunized10daystype II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) 69964type II collagen (2 mg/kg) Freund's incomplete adjuvant (50 %)
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8erythrocyte quantityRS:0000154BN/SsNboth139 days to 132 days208CMO:0000025red blood cell count9.47x 10E6 cells/ul0.0090.13MMO:0000146automated blood cell counting method0naive control condition65933naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8blood hemoglobin amountRS:0000154BN/SsNboth139 days to 132 days208CMO:0000026blood hemoglobin level17.2g/dl0.01390.2MMO:0000146automated blood cell counting method0naive control condition65915naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8erythrocyte size traitRS:0000154BN/SsNboth139 days to 132 days208CMO:0000038mean corpuscular volume55.3fl0.09711.4MMO:0000146automated blood cell counting method0naive control condition65921naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8erythrocyte quantityRS:0000154BN/SsNboth139 days to 132 days208CMO:0000037hematocrit52.4%0.11091.6MMO:0000146automated blood cell counting method0naive control condition65909naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8blood glucose amountRS:0000154BN/SsNboth125 days to 118 days220CMO:0000046blood glucose level116.64mg/dl1.504822.32MMO:0000164intraperitoneal glucose tolerance test0glucose injection120minglucose solution (2 g/kg) 65981glucose solution (2 g/kg)
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8blood glucose amountRS:0000154BN/SsNboth125 days to 118 days220CMO:0000046blood glucose level156.42mg/dl3.482951.66MMO:0000164intraperitoneal glucose tolerance test0glucose injection30minglucose solution (2 g/kg) 65975glucose solution (2 g/kg)
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8blood glucose amountRS:0000154BN/SsNboth125 days to 118 days220CMO:0000046blood glucose level108.54mg/dl1.019415.12MMO:0000164intraperitoneal glucose tolerance test0glucose injection0minglucose solution (2 g/kg) 65945glucose solution (2 g/kg)
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8heart massRS:0000154BN/SsNboth174 days to 167 days45CMO:0000074heart weight to body weight ratio3.4g/kg0.01940.13MMO:0000005post excision weight measurement0naive control condition65998naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8arterial blood pressure traitRS:0000154BN/SsNboth132 days to 125 days220CMO:0000004systolic blood pressure137mmHg1.078716.0MMO:0000053tail cuff piezoplethysmography6-8 readings per sittingnaive control condition11670naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8adrenal gland massRS:0000154BN/SsNboth174 days to 167 days210CMO:0000164both adrenal glands wet weight58mg0.36575.3MMO:0000005post excision weight measurement0naive control condition65985naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8body massRS:0000154BN/SsNboth70 days220CMO:0000012body weight246.1g0.54618.1MMO:0000016body weighing method0naive control condition66006naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology traitRS:0000154BN/SsNboth139 days to 132 days215CMO:0000603blood CD25 cell count to CD4 cell count ratio18.6%0.11661.71MMO:0000145automated differential white blood cell count test0naive control condition65902naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8adrenal gland massRS:0000154BN/SsNboth174 days to 167 days210CMO:0000621both adrenal glands weight to body weight ratio25.1mg/100g0.15872.3MMO:0000005post excision weight measurement0naive control condition65992naive control condition
1241Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50joint integrity traitRS:0000154BN/SsNfemale126 days to 66 days7CMO:0001456percentage of study population developing chronic experimental arthritis during a period of time0%MMO:0000163in vivo visual assessment0.0Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days)69924Freund's incomplete adjuvant (50 %) (between 1 and 7 days)type II collagen (2 mg/kg) (between 1 and 7 days)Freund's incomplete adjuvant (50 %) (between 1 and 35 days)type II collagen (100 ug) (between 1 and 35 days)
1241Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50joint integrity traitRS:0000154BN/SsNmale126 days to 66 days13CMO:0001456percentage of study population developing chronic experimental arthritis during a period of time0%MMO:0000163in vivo visual assessment0.0Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days)69923Freund's incomplete adjuvant (50 %) (between 1 and 7 days)type II collagen (2 mg/kg) (between 1 and 7 days)Freund's incomplete adjuvant (50 %) (between 1 and 35 days)type II collagen (100 ug) (between 1 and 35 days)
850Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89blood autoantibody amountRS:0000154BN/SsNboth126 days to 66 days13CMO:0001281calculated serum anti-rat type 2 collagen autoantibody titertiter20.55472.0MMO:0000075enzyme linked immunosorbent assay (ELISA)0.0variableimmunized10daystype II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) 69965type II collagen (2 mg/kg) Freund's incomplete adjuvant (50 %)
1241Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50blood autoantibody amountRS:0000154BN/SsNfemale126 days to 66 days7CMO:0001281calculated serum anti-rat type 2 collagen autoantibody titertiter1.90.68031.8MMO:0000075enzyme linked immunosorbent assay (ELISA)0.0Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) 69928Freund's incomplete adjuvant (50 %) type II collagen (2 mg/kg)
1241Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50blood autoantibody amountRS:0000154BN/SsNmale126 days to 66 days13CMO:0001281calculated serum anti-rat type 2 collagen autoantibody titertiter1.30.27741.0MMO:0000075enzyme linked immunosorbent assay (ELISA)0.0Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) 69927Freund's incomplete adjuvant (50 %) type II collagen (2 mg/kg)
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8CD4-positive T cell quantityRS:0000154BN/SsNboth139 days to 132 days211CMO:0000598blood CD4 cell count to CD8 cell count ratio2690%17.8303259.0MMO:0000145automated differential white blood cell count test0naive control condition65889naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8CD8-positive T cell quantityRS:0000154BN/SsNboth139 days to 132 days200CMO:0000597blood CD8 cell count0.12x 10E6 cells/ml0.00140.02MMO:0000145automated differential white blood cell count test0naive control condition65885naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8neutrophil quantityRS:0000154BN/SsNboth139 days to 132 days216CMO:0000030blood neutrophil count2.36x 1000 cells/ul0.04690.69MMO:0000145automated differential white blood cell count test0naive control condition65874naive control condition
114Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8CD4-positive T cell quantityRS:0000154BN/SsNboth139 days to 132 days203CMO:0000596blood CD4 cell count3.14x 1000 cells/ul0.05540.79MMO:0000145automated differential white blood cell count test0naive control condition65881naive control condition