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Rat Strains

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Experimental Conditions

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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1aCondition 1bCondition 2aCondition 2b
13body weight lossBN/SsNboth0%type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) 69958type II collagen (2 mg/kg) Freund's incomplete adjuvant (50 %)
208white blood cell countBN/SsNboth7.2x 1000 cells/ulnaive control condition65939naive control condition
207white blood cell countBN/SsNboth9.6x 1000 cells/ulnaive control condition65870naive control condition
208platelet countBN/SsNboth1037x 1000 cells/ulnaive control condition65927naive control condition
13percentage of study population developing experimental arthritis during a period of timeBN/SsNboth0%type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) 69961type II collagen (2 mg/kg) Freund's incomplete adjuvant (50 %)
13calculated serum anti-porcine type 2 collagen antibody titerBN/SsNboth3type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) 69964type II collagen (2 mg/kg) Freund's incomplete adjuvant (50 %)
208red blood cell countBN/SsNboth9.47x 10E6 cells/ulnaive control condition65933naive control condition
208blood hemoglobin levelBN/SsNboth17.2g/dlnaive control condition65915naive control condition
208mean corpuscular volumeBN/SsNboth55.3flnaive control condition65921naive control condition
208hematocritBN/SsNboth52.4%naive control condition65909naive control condition
220blood glucose levelBN/SsNboth116.64mg/dlglucose solution (2 g/kg) 65981glucose solution (2 g/kg)
220blood glucose levelBN/SsNboth156.42mg/dlglucose solution (2 g/kg) 65975glucose solution (2 g/kg)
220blood glucose levelBN/SsNboth108.54mg/dlglucose solution (2 g/kg) 65945glucose solution (2 g/kg)
45heart weight to body weight ratioBN/SsNboth3.4g/kgnaive control condition65998naive control condition
220systolic blood pressureBN/SsNboth137mmHgnaive control condition11670naive control condition
210both adrenal glands wet weightBN/SsNboth58mgnaive control condition65985naive control condition
220body weightBN/SsNboth246.1gnaive control condition66006naive control condition
215blood CD25 cell count to CD4 cell count ratioBN/SsNboth18.6%naive control condition65902naive control condition
210both adrenal glands weight to body weight ratioBN/SsNboth25.1mg/100gnaive control condition65992naive control condition
7percentage of study population developing chronic experimental arthritis during a period of timeBN/SsNfemale0%Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days)69924Freund's incomplete adjuvant (50 %) (between 1 and 7 days)type II collagen (2 mg/kg) (between 1 and 7 days)Freund's incomplete adjuvant (50 %) (between 1 and 35 days)type II collagen (100 ug) (between 1 and 35 days)
13percentage of study population developing chronic experimental arthritis during a period of timeBN/SsNmale0%Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days)69923Freund's incomplete adjuvant (50 %) (between 1 and 7 days)type II collagen (2 mg/kg) (between 1 and 7 days)Freund's incomplete adjuvant (50 %) (between 1 and 35 days)type II collagen (100 ug) (between 1 and 35 days)
13calculated serum anti-rat type 2 collagen autoantibody titerBN/SsNboth2type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) 69965type II collagen (2 mg/kg) Freund's incomplete adjuvant (50 %)
7calculated serum anti-rat type 2 collagen autoantibody titerBN/SsNfemale1.9Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) 69928Freund's incomplete adjuvant (50 %) type II collagen (2 mg/kg)
13calculated serum anti-rat type 2 collagen autoantibody titerBN/SsNmale1.3Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) 69927Freund's incomplete adjuvant (50 %) type II collagen (2 mg/kg)
211blood CD4 cell count to CD8 cell count ratioBN/SsNboth2690%naive control condition65889naive control condition
200blood CD8 cell countBN/SsNboth0.12x 10E6 cells/mlnaive control condition65885naive control condition
216blood neutrophil countBN/SsNboth2.36x 1000 cells/ulnaive control condition65874naive control condition
203blood CD4 cell countBN/SsNboth3.14x 1000 cells/ulnaive control condition65881naive control condition