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Study IDStudyExperiment NameExperiment NotesStrain Ont IDStrainSexAge# of AnimalsSample NotesClinical Measurement Ont IDPhenotypeFormulaClinical Measurement NotesAverage TypeValueUnitsSEMSDMethod Ont IDMethodMethod SiteMethod DurationMethod NotesPost Insult TypePost Insult Time ValuePost Insult Time UnitConditionsRecord IDCondition 1Condition 2Condition 3Condition 4Condition 5
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwifemale120 days to 87 days2CMO:0000533absolute change in mean arterial blood pressure-6.04mmHg3.134.4265MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)51130controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (for 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwimale120 days to 87 days7CMO:0000533absolute change in mean arterial blood pressure-1mmHg2.74837.2712MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)51135controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (for 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwifemale120 days to 87 days8CMO:0000533absolute change in mean arterial blood pressure1.5575mmHg1.66334.7046MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)51100controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwimale120 days to 87 days9CMO:0000533absolute change in mean arterial blood pressure0.4544mmHg3.08479.2541MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)51109controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000342FHH/EurMcwimale120 days to 87 days8CMO:0000533absolute change in mean arterial blood pressure-0.8125mmHg2.41476.8299MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)51085controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000342FHH/EurMcwimale120 days to 87 days8CMO:0000533absolute change in mean arterial blood pressure4.3738mmHg1.82195.1532MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)50995controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwifemale120 days to 87 days8CMO:0000533absolute change in mean arterial blood pressure2.8838mmHg1.84335.2135MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)50926controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (for 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwimale120 days to 87 days9CMO:0000533absolute change in mean arterial blood pressure-1.9822mmHg1.94385.8313MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)50935controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (for 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwifemale120 days to 87 days2CMO:0000533absolute change in mean arterial blood pressure4.245mmHg0.1250.1768MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)50914controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwimale120 days to 87 days7CMO:0000533absolute change in mean arterial blood pressure7.1586mmHg5.119913.5461MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)50919controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwifemale120 days to 87 days2CMO:0000533absolute change in mean arterial blood pressure2.52mmHg6.429.0793MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)50775controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwimale120 days to 87 days7CMO:0000533absolute change in mean arterial blood pressure0.9257mmHg2.3286.1592MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)50780controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwimale120 days to 87 days9CMO:0000533absolute change in mean arterial blood pressure-1.6978mmHg1.5934.7789MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)50608controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwifemale120 days to 87 days8CMO:0000533absolute change in mean arterial blood pressure0.5625mmHg1.17093.3119MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)50599controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000342FHH/EurMcwimale120 days to 87 days8CMO:0000533absolute change in mean arterial blood pressure0.4387mmHg2.74077.752MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)50435controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (for 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwifemale120 days to 87 days2CMO:0000533absolute change in mean arterial blood pressure4.62mmHg5.898.3297MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)51964controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwimale120 days to 87 days7CMO:0000533absolute change in mean arterial blood pressure13.5286mmHg3.991110.5595MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)51969controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwifemale120 days to 87 days8CMO:0000533absolute change in mean arterial blood pressure6.455mmHg2.32286.5699MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)51863controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwimale120 days to 87 days9CMO:0000533absolute change in mean arterial blood pressure7.1011mmHg2.79448.3833MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)51872controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwifemale120 days to 87 days8CMO:0000533absolute change in mean arterial blood pressure16.2188mmHg3.11348.8061MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)51768controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwimale120 days to 87 days9CMO:0000533absolute change in mean arterial blood pressure16.6944mmHg3.46410.3921MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)51777controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000342FHH/EurMcwimale120 days to 87 days8CMO:0000533absolute change in mean arterial blood pressure9.3188mmHg2.42396.8558MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)51740controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwifemale120 days to 87 days2CMO:0000533absolute change in mean arterial blood pressure25.88mmHg1.672.3617MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)51660controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwimale120 days to 87 days7CMO:0000533absolute change in mean arterial blood pressure30.9129mmHg4.22711.1835MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)51665controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataarterial blood pressure traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000342FHH/EurMcwimale120 days to 87 days8CMO:0000533absolute change in mean arterial blood pressure32.175mmHg4.699913.2934MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)51493controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwifemale120 days to 87 days2CMO:0000534absolute change in heart rate4.3beats/min93.3131.9461MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)51234controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwimale120 days to 87 days7CMO:0000534absolute change in heart rate-22.6571beats/min17.343945.8876MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)51239controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000342FHH/EurMcwimale120 days to 87 days8CMO:0000534absolute change in heart rate-9.45beats/min15.685244.3646MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)51216controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwifemale120 days to 87 days8CMO:0000534absolute change in heart rate-26.5313beats/min23.918267.651MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)50717controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwimale120 days to 87 days9CMO:0000534absolute change in heart rate-37.7078beats/min15.712347.1369MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)50726controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwifemale120 days to 87 days2CMO:0000534absolute change in heart rate-18.2beats/min46.265.3367MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)50681controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (for 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwimale120 days to 87 days7CMO:0000534absolute change in heart rate-5.2286beats/min21.306956.3729MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)50686controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (for 0.2 hours)
481PhysGen Renal A dataheart pumping traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000342FHH/EurMcwimale120 days to 87 days8CMO:0000534absolute change in heart rate-52.775beats/min23.984867.8392MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)50597controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwimale120 days to 87 days7CMO:0000534absolute change in heart rate-58.6857beats/min20.546154.3598MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)50588controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwifemale120 days to 87 days2CMO:0000534absolute change in heart rate-77.5beats/min34.749.0732MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)50583controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwifemale120 days to 87 days8CMO:0000534absolute change in heart rate11.1937beats/min19.046553.8715MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)50503controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (for 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwimale120 days to 87 days9CMO:0000534absolute change in heart rate-24.7656beats/min14.960644.8817MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)50512controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (for 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwifemale120 days to 87 days8CMO:0000534absolute change in heart rate-10.1812beats/min11.57532.739MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)50418controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwimale120 days to 87 days9CMO:0000534absolute change in heart rate-41.2989beats/min29.442688.3278MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)50427controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwifemale120 days to 87 days2CMO:0000534absolute change in heart rate-34.8beats/min65.492.4896MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)50356controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwimale120 days to 87 days7CMO:0000534absolute change in heart rate-65.0286beats/min16.815844.4905MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)50361controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000342FHH/EurMcwimale120 days to 87 days8CMO:0000534absolute change in heart rate-33beats/min25.61872.4588MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)50348controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000342FHH/EurMcwimale120 days to 87 days8CMO:0000534absolute change in heart rate-16.95beats/min18.349651.9005MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)50340controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwifemale120 days to 87 days8CMO:0000534absolute change in heart rate-11.0525beats/min21.230160.0478MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)52048controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwimale120 days to 87 days9CMO:0000534absolute change in heart rate-65.7433beats/min24.240572.7216MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)52057controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwifemale120 days to 87 days2CMO:0000534absolute change in heart rate21.3beats/min54.977.6403MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)51921controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed TekladRS:0000342FHH/EurMcwimale120 days to 87 days7CMO:0000534absolute change in heart rate-33.5714beats/min24.802165.6203MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)51926controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitConversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeksRS:0000342FHH/EurMcwimale120 days to 87 days8CMO:0000534absolute change in heart rate15.525beats/min17.938550.7378MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)51795controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (for 0.2 hours)norepinephrine (0.2 ng/kg/min) (for 0.2 hours)norepinephrine (0.5 ng/kg/min) (for 0.2 hours)norepinephrine (1 ng/kg/min) (for 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwifemale120 days to 87 days8CMO:0000534absolute change in heart rate2.1688beats/min10.27929.0734MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)51367controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)
481PhysGen Renal A dataheart pumping traitMoms and pups used in studies were fed DyetsRS:0000342FHH/EurMcwimale120 days to 87 days9CMO:0000534absolute change in heart rate-49.0444beats/min15.901647.7049MMO:0000013vascular fluid filled cathetercontrolled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)51376controlled sodium content diet (4 %) (between 24 and 31 days)norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)