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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1aCondition 1bCondition 2aCondition 2bCondition 3aCondition 3bCondition 4Condition 5Condition 6
5logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwifemale-8.295phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)55496phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
5logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwimale-8.0199phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)55499phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
6logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwifemale-8.2912controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)55485controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
6logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwimale-8.6692controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)55491controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
2logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwimale-8.5925phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)54619phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
5logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwifemale-8.5086controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56016controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
11logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwimale-8.2075controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56028controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
6logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwifemale-8.5517phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56000phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
5logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwimale-8.9184phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56006phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
6maximum contractile force per wet weight of aortaFHH/EurMcwifemale1.9017g/mgcontrolled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)63166controlled sodium content diet (4 %) (for 14 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
117maximum contractile force per wet weight of aortaFHH/EurMcwimale1.3081g/mgcontrolled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)63177controlled sodium content diet (4 %) (for 14 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
10maximum contractile force per wet weight of aortaFHH/EurMcwifemale1.76g/mgcontrolled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)57348controlled sodium content diet (4 %) (for 21 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
55maximum contractile force per wet weight of aortaFHH/EurMcwimale1.0305g/mgcontrolled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)57367controlled sodium content diet (4 %) (for 21 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
10maximum contractile force per wet weight of aortaFHH/EurMcwifemale1.23g/mgcontrolled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)56984controlled sodium content diet (4 %) (for 21 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
10maximum contractile force per wet weight of aortaFHH/EurMcwimale1.361g/mgcontrolled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)56990controlled sodium content diet (4 %) (for 21 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
49maximum contractile force per wet weight of aortaFHH/EurMcwimale1.0806g/mgpotassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)55821potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
9maximum contractile force per wet weight of aortaFHH/EurMcwifemale1.51g/mgpotassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)55802potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
5maximum contractile force per wet weight of aortaFHH/EurMcwifemale1.942g/mgpotassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)55010potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
5maximum contractile force per wet weight of aortaFHH/EurMcwimale1.726g/mgpotassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)55013potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
12maximum contractile force per wet weight of aortaFHH/EurMcwifemale1.5617g/mgpotassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)56215potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
8maximum contractile force per wet weight of aortaFHH/EurMcwimale1.2175g/mgpotassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)56221potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
5concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwifemale0.0569E-7molephenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56809phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
5concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwimale0.0908E-7molephenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56812phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
6concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwifemale0.0862E-7molephenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56693phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
5concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwimale0.0141E-7molephenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56699phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
2concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwimale0.0263E-7molephenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)55745phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
6concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwifemale0.2557E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56260controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
6concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwimale0.0259E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56266controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
5concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwifemale0.0329E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56228controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
11concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwimale0.1014E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56240controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
10concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwifemale1.4528E-7molephenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)56786phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
5concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwimale0.6256E-7molephenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)56792phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
10concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwifemale1.5838E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)56534controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
50concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwimale1.3813E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)56553controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
6concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwifemale1.197E-7molecontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)63029controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
112concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwimale1.312E-7molecontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)63038controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
5concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwifemale0.995E-7molephenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)57127phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
5concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwimale1.8032E-7molephenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)57130phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
8concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwifemale1.3372E-7molephenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)55908phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
46concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwimale1.6654E-7molephenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)55927phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
7concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwifemale0.9222E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)54589controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
7concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH/EurMcwimale1.3843E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)54595controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
6logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwifemale-8.1092controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)63097controlled sodium content diet (4 %) (for 14 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
119logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwimale-8.1504controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)63108controlled sodium content diet (4 %) (for 14 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
8logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwifemale-6.1765controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)55720controlled sodium content diet (4 %) (for 21 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
8logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwimale-6.2629controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)55726controlled sodium content diet (4 %) (for 21 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
10logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwifemale-7.3723phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)55705phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
6logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwimale-7.4738phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)55711phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
8logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwifemale-8.3539phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)55289phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
50logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwimale-7.8613phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)55308phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
5logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwifemale-7.3944phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)56173phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
5logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwimale-7.5624phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)56176phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
10logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwifemale-7.7571controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)56119controlled sodium content diet (4 %) (for 21 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
54logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH/EurMcwimale-7.8459controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)56138controlled sodium content diet (4 %) (for 21 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
6concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwifemale0.0094E-6molecontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)62774controlled sodium content diet (4 %) (for 14 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
119concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwimale0.0129E-6molecontrolled sodium content diet (4 %) (for 14 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)62785controlled sodium content diet (4 %) (for 14 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
8concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwifemale0.7388E-6molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)56876controlled sodium content diet (4 %) (for 21 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
8concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwimale0.6332E-6molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)56882controlled sodium content diet (4 %) (for 21 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
5concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwifemale0.0428E-6molephenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)55124phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
5concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwimale0.0322E-6molephenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)55127phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
10concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwifemale0.0523E-6molephenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)54987phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
6concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwimale0.0466E-6molephenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)54993phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
10concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwifemale0.0239E-6molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)54920controlled sodium content diet (4 %) (for 21 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
54concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwimale0.0508E-6molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)54939controlled sodium content diet (4 %) (for 21 days)phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
8concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwifemale0.0079E-6molephenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)54688phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
50concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH/EurMcwimale0.0174E-6molephenylephrine (0~300 umol/l) and drug dose time series (for 1.2 hours)54707phenylephrine (0~300 umol/l) drug dose time series (for 1.2 hours)
10acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale78.3%phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)56841phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
6acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale88.6667%phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)56847phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
6acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale80.3333%controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)62629controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
111acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale65.3423%controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)62638controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
5acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale55.8%phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)57296phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
5acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale61.4%phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)57299phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
8acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale61.5%phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)57238phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
47acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale71.4894%phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)57257phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
7acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale84.8571%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)55101controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
7acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale85%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)55107controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
9acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale61.4444%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)54794controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
50acetylcholine-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale71.46%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)54813controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
6logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwifemale-7.0863controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)62852controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
112logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwimale-6.9991controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)62861controlled sodium content diet (4 %) (for 14 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
7logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwifemale-7.495controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)57403controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
7logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwimale-7.0874controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)57409controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
9logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwifemale-6.8599controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)56929controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
50logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwimale-6.9339controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)56948controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
8logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwifemale-6.91phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)55639phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
47logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwimale-6.8693phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)55658phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
5logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwifemale-7.105phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)55369phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
5logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwimale-6.7624phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)55372phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
10logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwifemale-7.1519phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)55020phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
5logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH/EurMcwimale-7.2728phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0~30 umol/l) and drug dose time series (for 1 hours)55026phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0~30 umol/l) drug dose time series (for 1 hours)
3hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale42%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)56728phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)
5hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale42%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)56731phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)
9hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale41%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)56715controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)
10hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale46.3%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)56721controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)
3hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale55%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)57178phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)
5hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale56%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)57134controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)
9hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale40%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)57146controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)
11hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale49.1818%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)55356phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)
6hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale39.8333%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)55362phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)
3hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale32.3333%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)55143phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)
5hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale14.4%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)55071controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)
9hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale17%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)55083controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)
3hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale36%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)55055phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)
11hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale38.7273%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)54975phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)
6hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale33.1667%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)54981phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)
9hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale26.5556%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)54849controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)
10hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale33.6%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)54855controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)
3hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale19.6667%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)55989phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)
5hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale24.6%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)55992phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)
9hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale75.5556%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)56439controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)
10hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale87.3%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)56445controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)
11hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale64.0909%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)56333phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)
6hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale62.1667%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)56339phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)
5hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale32.2%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)56271controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)
9hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale26.1111%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)56283controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)
3hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale11%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)56205phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)
5hypoxia-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale14.6%phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)56208phenylephrine (1 umol/l) controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours)controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)
2sodium nitroprusside-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale100%phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56475phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
8sodium nitroprusside-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale99.375%phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)55965phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
5sodium nitroprusside-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale99.6%phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)55971phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
5sodium nitroprusside-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale99.8%phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)55376phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
5sodium nitroprusside-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale98.6%phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)55379phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
5sodium nitroprusside-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale97.6%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56303controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
11sodium nitroprusside-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale95%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56315controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
8sodium nitroprusside-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwifemale99%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56194controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)
10sodium nitroprusside-induced blood vessel dilation expressed as percent of force at maximum constrictionFHH/EurMcwimale100%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0~3 umol/l) and drug dose time series (for 1 hours)56200controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)sodium nitroprusside (0~3 umol/l) drug dose time series (for 1 hours)