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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 11297
Species: Mus musculus
CRRD Object: Gene
Symbol: Slc12a1
Name: solute carrier family 12, member 1
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:36856480464CTDCarbon Tetrachloride results in decreased expression of SLC12A1 mRNA

PMID:17805973
increases expressionISORGD:36856480464CTDCarbon Tetrachloride results in increased expression of SLC12A1 mRNA, Carbon Tetrachloride results in increased expression of SLC12A1 protein

PMID:15673309, PMID:16192424, PMID:16644059
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.