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GENE - TERM ANNOTATION REPORT

CRRD ID: 11834437
Species: Pan paniscus
CRRD Object: Gene
Symbol: PTEN
Name: phosphatase and tensin homolog
Acc ID: DOID:9008443
Term: Colorectal Neoplasms
Definition: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
Definition Source(s): MESH:D015179
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 ISSCRRD:691199068941ClinVarClinVar Annotator: match by term: Colorectal Neoplasms

PMID:10400993, PMID:10555148, PMID:10920277, PMID:10923032, PMID:11504908, PMID:15016963, PMID:15211648, PMID:15254419, PMID:15647370, PMID:16952599, PMID:17526800, PMID:18558293, PMID:18725974, PMID:19351834, PMID:19366826, PMID:19903786, PMID:20018398, PMID:20085938, PMID:20453058, PMID:20619739, PMID:20881644, PMID:21194675, PMID:21956414, PMID:22162582, PMID:22162589, PMID:22479427, PMID:23335809, PMID:23470840, PMID:23475934, PMID:24778394, PMID:25288137, PMID:25741868, PMID:27426521, PMID:28286253, PMID:28492532, PMID:28526761, PMID:9140396, PMID:9241266, PMID:9259288, PMID:9598803
 ISSCRRD:691199068941ClinVarClinVar Annotator: match by term: Colorectal Neoplasms

PMID:10555148, PMID:11504908, PMID:15016963, PMID:15254419, PMID:15647370, PMID:17526800, PMID:18725974, PMID:19366826, PMID:19903786, PMID:20085938, PMID:20453058, PMID:20619739, PMID:21194675, PMID:21956414, PMID:22162582, PMID:22162589, PMID:27477328, PMID:27626691, PMID:28492532
 ISSCRRD:691199068941ClinVarClinVar Annotator: match by term: Colorectal Neoplasms

PMID:10555148, PMID:11504908, PMID:15016963, PMID:15254419, PMID:15647370, PMID:18725974, PMID:19366826, PMID:19903786, PMID:20085938, PMID:20453058, PMID:20619739, PMID:22162582, PMID:22162589
 ISSCRRD:691199068941ClinVarClinVar Annotator: match by term: Colorectal Neoplasms

PMID:10866302, PMID:11504908, PMID:11875759, PMID:16773562, PMID:17526801, PMID:17942903, PMID:18767981, PMID:19457929, PMID:20085938, PMID:20300775, PMID:21659347, PMID:21822720, PMID:21828076, PMID:22266152, PMID:22320991, PMID:22327138, PMID:22595938, PMID:23335809, PMID:23399955, PMID:23470840, PMID:24778394, PMID:25157968, PMID:25527629, PMID:26619011, PMID:26798346, PMID:27477328, PMID:28492532, PMID:9467011, PMID:9915974
 ISSCRRD:691199068941ClinVarClinVar Annotator: match by term: Colorectal Neoplasms

PMID:11504908, PMID:18767981, PMID:20085938, PMID:21824802, PMID:25157968, PMID:26619011
 ISSCRRD:691199068941ClinVarClinVar Annotator: match by term: Colorectal Neoplasms

PMID:21659347, PMID:23335809, PMID:24778394, PMID:25527629, PMID:25741868, PMID:26619011, PMID:9467011
 ISSCRRD:691199068941ClinVarClinVar Annotator: match by term: Colorectal Neoplasms

PMID:21828076, PMID:22266152, PMID:26619011, PMID:28492532, PMID:9467011
 ISSCRRD:691199068941ClinVarClinVar Annotator: match by term: Colorectal Neoplasms

PMID:26619011, PMID:28492532
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.