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CRRD ID: 12060975
Species: Canis lupus familiaris
CRRD Object: Gene
Symbol: SHROOM1
Name: shroom family member 1
Acc ID: GO:0043296
Term: apical junction complex
Definition: A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
Definition Source(s): GOC:go_curators, GOC:kmv, PMID:12525486, PMID:15196556
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SHROOM1 IBAMGI:MGI:107194, MGI:MGI:1351655, PANTHER:PTN00038516413508589GO_Central (PMID:21873635)

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.