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GENE - TERM ANNOTATION REPORT

CRRD ID: 12116841
Species: Canis lupus familiaris
CRRD Object: Gene
Symbol: RB1CC1
Name: RB1 inducible coiled-coil 1
Acc ID: GO:1990316
Term: Atg1/ULK1 kinase complex
Definition: A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.
Definition Source(s): GOC:bhm, GOC:DOS, GOC:rb, PMID:15743910, PMID:19211835, PMID:19258318, PMID:19597335, PMID:22885598
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RB1CC1 IBAFB:FBgn0037363, MGI:MGI:1341850, PANTHER:PTN000996416, UniProtKB:Q8TDY213508589GO_Central (PMID:21873635)

PMID:21873635
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.