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CRRD ID: 12273496
Species: Canis lupus familiaris
CRRD Object: Gene
Symbol: PRDX4
Name: peroxiredoxin 4
Acc ID: GO:0006979
Term: response to oxidative stress
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
Definition Source(s): GOC:jl, PMID:12115731
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRDX4 IBACGD:CAL0000174369, FB:FBgn0040308, FB:FBgn0040309, MGI:MGI:99523, PANTHER:PTN000073874, RGD:3838, RGD:620039, SGD:S000002861, SGD:S000004490, UniProtKB:P0AE08, UniProtKB:P0CU34, UniProtKB:P32119, UniProtKB:Q8I5Q6, UniProtKB:Q8IL8013508589GO_Central (PMID:21873635)

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.