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GENE - TERM ANNOTATION REPORT

CRRD ID: 12275579
Species: Canis lupus familiaris
CRRD Object: Gene
Symbol: ALOXE3
Name: arachidonate lipoxygenase 3
Acc ID: GO:0051120
Term: hepoxilin A3 synthase activity
Definition: Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.
Definition Source(s): PMID:15123652
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALOXE3 IEAUniProtKB:Q9WV07, ensembl:ENSMUSP0000002126813508589Ensembl GO_REF:0000107
ALOXE3 IBAMGI:MGI:1345140, PANTHER:PTN000206222, UniProtKB:Q9BYJ113508589GO_Central (PMID:21873635)

PMID:21873635
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