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GENE - TERM ANNOTATION REPORT

CRRD ID: 12572776
Species: Ictidomys tridecemlineatus
CRRD Object: Gene
Symbol: Ago2
Name: argonaute RISC catalytic component 2
Acc ID: GO:0000932
Term: P-body
Definition: A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
Definition Source(s): GOC:clt, PMID:12730603
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ago2 ISORGD:7327689068941MGI (MGI:MGI:4438512, PMID:19898466)

MGI:MGI:4438512, PMID:19898466
Ago2 ISORGD:7327679068941UniProtKB (PMID:20616046), (PMID:22915799), (PMID:23125361)

PMID:20616046, PMID:22915799, PMID:23125361
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.