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GENE - TERM ANNOTATION REPORT

CRRD ID: 12605623
Species: Ictidomys tridecemlineatus
CRRD Object: Gene
Symbol: Egln3
Name: egl-9 family hypoxia inducible factor 3
Acc ID: PW:0000360
Term: hypoxia inducible factor pathway
Definition: The hypoxia inducible transcription factor is activated in response to hypoxic conditions to promote the expression of many genes that play important roles in glucose and energy metabolism, angiogenesis and erythropoiesis.
Definition Source(s): PMID:11181957, PMID:12603312, PMID:14597660, PMID:15031665
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Egln3 ISORGD:7326529068941CRRD PMID:14597660, PMID:20396958, REF_RGD_ID:1334466, REF_RGD_ID:6483503
Egln3 ISORGD:7326529068941PID PID:200036, PID:200202
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.