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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1303314
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Uqcrc1
Name: ubiquinol-cytochrome c reductase core protein 1
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13425996480464CTDresveratrol results in increased expression of UQCRC1 protein

PMID:24365713
increases expressionISORGD:15518476480464CTDresveratrol results in increased expression of UQCRC1 protein

PMID:24041027
multiple interactionsISORGD:13425996480464CTD1H-(1, 2, 4)oxadiazolo(4, 3-a)quinoxalin-1-one inhibits the reaction [resveratrol results in increased expression of UQCRC1 protein], HMOX1 mutant form inhibits the reaction [resveratrol results in increased expression of UQCRC1 protein], lipopolysaccharide, E coli O55-B5 promotes the reaction [resveratrol results in increased expression of UQCRC1 protein], resveratrol promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of UQCRC1 protein], tin protoporphyrin IX inhibits the reaction [lipopolysaccharide, E coli O55-B5 promotes the reaction [resveratrol results in increased expression of UQCRC1 protein]], tin protoporphyrin IX inhibits the reaction [resveratrol promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of UQCRC1 protein]], tin protoporphyrin IX inhibits the reaction [resveratrol results in increased expression of UQCRC1 protein]

PMID:24041027
multiple interactionsISORGD:15518476480464CTDResveratrol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of UQCRC1 protein], tin protoporphyrin IX inhibits the reaction [Resveratrol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of UQCRC1 protein]], tin protoporphyrin IX inhibits the reaction [Resveratrol results in increased expression of UQCRC1 protein]

PMID:24041027
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.