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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1305588
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Rag2
Name: recombination activating 2
Acc ID: CHEBI:34591
Term: bromodichloromethane
Definition: A halomethane that is dichloromethane in which oneof the hydrogens has been replaced by a bromine atom. It occurs as a contaminant in drinking water.
Chemical ID: MESH:C025191
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rag2multiple interactionsISORGD:13137076480464CTD[PRF1 protein co-treated with RAG2 protein] affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of CASP3 protein modified form], [PRF1 protein co-treated with RAG2 protein] affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA], [PRF1 protein co-treated with RAG2 protein] affects the susceptibility to [bromodichloromethane co-treated with Dietary Fats]

PMID:24211274
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.