GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1306661
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Chuk
Name: component of inhibitor of nuclear factor kappa B kinase complex
Acc ID: CHEBI:46666
Term: crocidolite asbestos
Definition: null
Chemical ID: MESH:D017638
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:13154016480464CTDAsbestos, Crocidolite results in increased activity of and results in increased phosphorylation of CHUK protein

Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite results in increased activity of and results in increased phosphorylation of CHUK protein]

PMID:17322126
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.