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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1307026
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Slc39a14
Name: solute carrier family 39 member 14
Acc ID: CHEBI:18248
Term: iron atom
Definition: An iron group element atom that has atomic number 26.
Chemical ID: MESH:D007501
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13159766480464CTDIron results in increased expression of SLC39A14 mRNA, Iron results in increased expression of SLC39A14 protein

PMID:24569067
increases importISORGD:13159766480464CTDSLC39A14 protein results in increased import of Iron

PMID:22898811
increases uptakeISORGD:13159766480464CTDSLC39A14 protein results in increased uptake of Iron

PMID:16950869
multiple interactionsISORGD:13159766480464CTD4, 7-diphenylphenanthroline sulfonate inhibits the reaction [SLC39A14 protein results in increased uptake of Iron], [Ethanol co-treated with Iron] results in increased expression of SLC39A14 mRNA, [Ethanol co-treated with Iron] results in increased expression of SLC39A14 protein, Quercetin inhibits the reaction [[Ethanol co-treated with Iron] results in increased expression of SLC39A14 mRNA], Quercetin inhibits the reaction [[Ethanol co-treated with Iron] results in increased expression of SLC39A14 protein], Quercetin inhibits the reaction [Iron results in increased expression of SLC39A14 mRNA], Quercetin inhibits the reaction [Iron results in increased expression of SLC39A14 protein]

PMID:16950869, PMID:24569067
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.