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GENE - TERM ANNOTATION REPORT

CRRD ID: 1308354
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ptpa
Name: protein phosphatase 2 phosphatase activator
Acc ID: GO:0000159
Term: protein phosphatase type 2A complex
Definition: A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
Definition Source(s): GOC:mah, ISBN:0198547684, PMID:17245430
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAPANTHER:PTN000000630, SGD:S000006073, UniProtKB:Q1525713792537GO_CentralPMID:21873635

 
 ISORGD:13180761624291CRRD (PMID:10318862)

PMID:10318862
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.