GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1309460
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ddx58
Name: DEXD/H-box helicase 58
Acc ID: CHEBI:63623
Term: succimer
Definition: A sulfur-containing carboxylic acid that is succinic acid bearing two mercapto substituents at positions 2 and 3. A lead chelator used as an antedote to lead poisoning.
Chemical ID: MESH:D004113
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:13198126480464CTD[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of DDX58 mRNA

PMID:26378955
multiple interactionsISOCRRD:13198136480464CTD[Succimer binds to Magnetite Nanoparticles] which results in increased expression of DDX58 mRNA

[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of DDX58 mRNA

PMID:21641980, PMID:26378955
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.