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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1309970
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gsta4
Name: glutathione S-transferase alpha 4
Acc ID: CHEBI:16856
Term: glutathione
Definition: A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
Chemical ID: MESH:D005978
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects metabolic processingEXP 6480464CTDGSTA4 protein affects the metabolism of Glutathione

PMID:14727915
affects metabolic processingISORGD:13206016480464CTDGSTA4 protein affects the metabolism of Glutathione

PMID:14727915
multiple interactionsISORGD:13206016480464CTD[GSTA4 protein co-treated with Glutathione] results in increased metabolism of amodiaquine quinoneimine, [GSTA4 protein co-treated with Glutathione] results in increased metabolism of desethylamodiaquine

PMID:28478157
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.