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CRRD ID: 1312654
Species: Homo sapiens
CRRD Object: Gene
Symbol: RUBCNL
Name: rubicon like autophagy enhancer
Acc ID: GO:0097352
Term: autophagosome maturation
Definition: Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling.
Definition Source(s): GOC:autophagy, GOC:lf, PMID:28077293
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAMGI:MGI:2685590, PANTHER:PTN002915558, UniProtKB:Q9H7142290271GO_Central (PMID:21873635)

 IDA 2290271UniProt (PMID:28306502), (PMID:30704899)

PMID:28306502, PMID:30704899
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.